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Another recently emerging option is plant-derived nanoparticles (NPs), which can be easily produced at high levels at relatively low cost
Using this knowledge, researchers from Tokyo University of Science (TUS) have recently developed bionanoparticles with anticancer activity, using corn as a raw material
After the team mixed the super sweet corn evenly in water, the corn juice was centrifuged at high speed and then filtered through a syringe filter with a pore size of 0.
The team then conducted experiments to see if these cNPs were taken up by various types of cells
The results were striking: Of the three cell types, the cNPs only significantly inhibited the growth of colon 26 cells, indicating selectivity for oncogenic cell lines
The research group conducted reporter experiments with the sensitive reporter enzyme "luciferase" that studies various biological reactions
"By optimizing the properties of nanoparticles and combining them with anticancer drugs, we hope to design safe and effective drugs to treat various cancers," said Prof.
Summarizing these impactful findings, Dr.
Journal Reference :
Daisuke Sasaki, Kosuke Kusamori, Yukiya Takayama, Shoko Itakura, Hiroaki Todo, Makiya Nishikawa.
