With cancer death rates down 32% and more than 18 million survivors, what is cancer treatment right in the United States?

At the end of September this year, the American Association for Cancer Research (AACR) released the 12th edition (2022 edition) of its annual cancer progress report
.
The report shows that between 1991 and 2019, cancer mortality fell by 32%, an average annual decline of 2.
3%, of which the death rate of lung cancer in men has decreased by 53% from the 90s to the present, and in recent years it has decreased by an average of 5%
per year.

As of January 2022, more than 18 million cancer survivors live in the United States
.
And cancer mortality rates continue to decline, at an accelerating
rate.

▲ Cancer mortality rate in the United States fell by 32%, source: reference source [1]

How did the U.
S.
manage to reduce cancer mortality year after year?

01

Prevention of carcinogenic factors

Studies have shown that more than 40% of cancer cases are linked to preventable factors, including smoking, poor diet, lack of exercise and obesity
.

Therefore, effective prevention of carcinogenic factors can reduce cancer mortality
.

Among all the carcinogenic factors, the first is the promotion of smoking cessation, and the number of smokers in the United States fell from 32% in 1982 to 17%
in 2007.
At the same time, vaccination of hepatitis B vaccine, HPV vaccine and other vaccines effectively reduces the cancer caused by the
virus.
In addition, environmental protection is getting better
and better.

In addition, obesity and alcohol consumption are also important factors in increasing cancer incidence and mortality year by year, so maintaining a healthy weight, exercising, eating a balanced diet and limiting alcohol consumption or non-alcohol are effective ways to
reduce cancer risk.

02

Promote early diagnosis and early treatment

As we all know, most cancer patients are diagnosed in the middle and advanced stages, and the mortality rate is extremely high
.
If cancer can be detected early and treated in time, it will greatly improve the survival rate
of cancer patients.

Early detection of cancer and early treatment through early tumor screening is the most effective means
of reducing mortality.

At present, lung cancer, breast cancer, colorectal cancer, prostate cancer, cervical cancer and other cancer screening have entered the US national and commercial medical insurance, making people's cancer prevention screening more convenient and improving the early detection rate
of cancer.

03

Approval of innovative therapies

Surgery, radiotherapy, chemotherapy, molecularly targeted therapy, and immunotherapy are the five pillars
of cancer treatment.
In these areas, advances in innovative approaches are saving the lives
of more cancer patients.

According to the report, in the past year, the US FDA has approved 8 innovative anti-cancer therapies, expanding the applicable cancer types
of 10 anti-cancer therapies.

▲Innovative anti-cancer therapy approved by the FDA from August 2021 to July 2022, source: reference source [1]

These include Pluvicto, the first targeted radioligand therapy combining isotope therapy with targeted compounds, Pluvicto (formerly known as 177Lu-PSMA-617); The first LAG-3 antibody and Relatlimab, the first innovative cancer immunotherapy approved for new immune checkpoints in nearly a decade; Welireg (belzutifan), the first molecularly targeted therapy to treat cancer patients with Von Hippel-Lindau syndrome, a rare genetic disorder; The first drug to treat uveal melanoma, a common eye cancer in adults, and so on
.

In addition, there have been in-depth research and exciting developments
in the clinical application of AI (artificial intelligence).
To that end, the FDA has approved a number of AI-based tools to help clinicians detect cancer earlier and provide a more complete diagnosis to improve cures
.

▲Source: Maker Post

Multidisciplinary treatment becomes the best means of cancer treatment

In the face of cancer, the best treatment is to use surgery, radiotherapy, and drug treatment just right
.
Just like a battle, intelligence, positioning, attacking, cleaning the battlefield, and restoring normal order must have a specific method
for each step.

There is no good medicine for all diseases, only a key and a lock to solve the problems one by one
.
And the doctor, like a general who formulates a battle plan on the battlefield, must clarify what the enemy is facing, where to hide, what methods are needed to attack, the advantages and disadvantages of each treatment, the short-term and long-term effects and costs, and what means are needed to restore the normal state in the future, in order to truly achieve the fight against cancer!

Hospitals in the United States attach great importance to multidisciplinary diagnosis and treatment, and after the results of the examination, the first step is to conduct a comprehensive tumor committee discussion, discuss the treatment methods suitable for patients, and formulate standardized and individualized treatment plans
.

1

standardization

The National Comprehensive Cancer Network publishes various malignant neoplasm clinical practice guidelines (NCCN guidelines) every year, and the American Society of Clinical Oncology compiles ASCO clinical practice guidelines covering breast cancer, gastrointestinal cancer, genitourinary cancer, head and neck cancer, hematological malignancies, melanoma, neuro-oncology and lung cancer
。

2

Individualization

American doctors treat each cancer patient as an individual and conduct multidisciplinary consultation, including members of surgery, medical oncology, radiotherapy, pathology, and imaging; Develop a comprehensive individualized treatment plan to avoid blind, inefficient, and even wrong treatment
.

Based on this, the cure rate of cancer in the United States is steadily improving, and according to data released by the American Cancer Society (ACS) and the National Cancer Institute (NCI) in June 2022, the overall 5-year survival rate for cancer has reached 69%[2] (40.
5% in China[3]
).

Which patients are suitable for medical treatment in the United States?

As a well-known overseas medical service institution in China, HOPU Ark has provided remote consultation services for countless patients and their families who are preparing to go abroad for medical treatment, so that patients and their families can obtain the diagnosis and treatment
of world-renowned experts without leaving home.
In addition, the "green channel for overseas medical treatment" retained by HOPU Ark has provided assistance
to many patients who are preparing to go abroad to see a doctor during the epidemic.
At present, there is no need to quarantine to travel to the United States for medical treatment, which provides convenience for many patients who are preparing for medical treatment
.

For patients and their families who are ready to go to the United States for medical treatment, but do not know much about relevant policies, they can also apply for visas and make hospital appointments with the help of HOPU Ark, which can help patients and their families to rush to the United States in the fastest time and carry out treatment
as soon as possible.

If you are interested in traveling to the United States for medical treatment or want to know more about overseas medical treatment, you can call the toll-free hotline 400-081-6600 or add WeChat DrHopeNoah to contact us
.

Reference source:

[1] AACR Cancer Progress Report - Cancer Progress Report

https://cancerprogressreport.
aacr.
org/progress/

https://cancerprogressreport.
aacr.
org/wp-content/uploads/sites/2/2022/09/AACR_CPR_2022.
pdf

[2] Miller KD, Nogueira L, Devasia T, Mariotto AB, Yabroff KR, Jemal A, Kramer J, Siegel RL.
Cancer treatment and survivorship statistics, 2022.
CA Cancer J Clin.
2022 Jun 23.
doi: 10.
3322/caac.
21731.
Epub ahead of print.
PMID: 35736631.

[3] Zeng H, Chen W, Zheng R, et al.
Changing cancer survival in China during 2003–15: a pooled analysis of 17 population-based cancer registries[J].
The Lancet Global Health, 2018, 6(5): e555-e567.

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