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    Home > Active Ingredient News > Antitumor Therapy > Why does the risk of colorectal cancer increase?

    Why does the risk of colorectal cancer increase?

    • Last Update: 2021-04-23
    • Source: Internet
    • Author: User
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    ▎The content team editor of WuXi AppTec.
    According to data released by the International Agency for Research on Cancer (IARC) of the World Health Organization, in 2020, 1.
    93 million new cases of colorectal cancer occurred globally and caused approximately 940,000 deaths; the number of new cases and deaths, respectively Ranked 2nd and 3rd in the number of new cancers and deaths in the world.

    The colorectal is a part of the digestive system, and the occurrence of colorectal cancer has a lot to do with diet.

    A new study recently published in the journal Clinical Nutrition reveals that a type of food is associated with an increased risk of colorectal cancer.

    Image source: 123RF researchers from the Barcelona Institute of Global Health (ISGlobal) analyzed data from 12 provinces in Spain and included 7834 subjects between the ages of 20 and 85.

    Among them, 4291 people have cancer, including colorectal cancer (1852), breast cancer (1486) and prostate cancer (953); 3543 people are healthy controls matched according to the age, gender and region of cancer patients.

    Through the questionnaire, the researchers collected the subjects’ age, gender, education level, alcohol consumption, smoking status, physical activity, disease history, etc.
    , as well as the consumption and frequency of different foods in the past year, such as vegetables, Fruits, whole grains and ultra-processed foods, etc.

    In this study, ultra-processed foods refer to foods that have been processed many times, and industrial formulas containing more than five ingredients, usually containing sugar, fat, salt and additives and other substances.

    Ultra-processed foods include sugary drinks, sugary foods, ready-to-eat foods and mass-produced industrial baked goods.

    Statistics found that among the ultra-processed foods consumed by the subjects, sugar-sweetened beverages (35%) accounted for the largest proportion, followed by sugar-sweetened foods (19%), ready-to-eat foods (16%) and processed meats (12%).
    %).Image source: 123RF After adjusting for other factors, researchers found that the consumption of ultra-processed foods is associated with a higher risk of colorectal cancer.

    Every 10% increase in the consumption of ultra-processed foods is associated with an 11% increase in the risk of colorectal cancer.

    Researchers analyzed that the association between eating ultra-processed foods and increased risk of colorectal cancer may be related to many reasons.
    For example, people who eat a lot of ultra-processed foods consume less dietary fiber, fruits and vegetables, and these Food has the effect of preventing colorectal cancer; in addition, additives contained in ultra-processed foods or other substances with cancer risk may also increase the risk of colorectal cancer.

    Among subjects with breast and prostate cancer, the researchers did not find a significant association between the consumption of processed foods and an increased risk of related cancers.

    However, among current and former smokers, researchers have found that eating processed foods is associated with an increased risk of breast cancer.

    Researchers believe that this may be because smoking is a risk factor for breast cancer, and people have found that actual smoking and certain dietary factors, such as eating processed foods, may have a synergistic effect on the occurrence and development of cancer.

    Since the study is an observational study, it only shows that the consumption of processed foods is associated with an increased risk of colorectal cancer, and does not show a causal relationship.

    Image source: 123RF researchers pointed out that social, economic and industrial changes have promoted the increase in the consumption of ultra-processed foods.
    At present, ultra-processed foods account for 25%-50% of the total energy intake in the diets of high-income and middle-income countries .

    Previous studies have revealed the health hazards of eating ultra-processed foods, such as cardiovascular disease, type 2 diabetes and increased risk of all-cause death.

    This research adds new evidence that ultra-processed foods are harmful to health.

    Based on the results of this study and the current evidence on the increased health risks of eating processed foods, especially cancer risks, the researchers emphasized that the consumption of processed foods should be restricted, and whole grains, vegetables, fruits, soybeans and their products, milk and The consumption of its products, fish meat, nuts, drinking water (tea drinking) and other foods allows fresh or least processed foods to form three meals a day, which promotes the improvement of overall health.

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    [1] Dora Romaguera, et al.
    ,(2021).
    Consumption of ultra-processed foods and drinks and colorectal, breast, and prostate cancer.
    Clinical Nutrition, DOI:https://doi.
    org/10.
    1016/j.
    clnu.
    2021.
    02.
    033.
    [2] Association found between consumption of ultra-processed foods and drinks and colorectal cancer risk.
    Retrieved Apr 19 ,2021,from https: //medicalxpress.
    com/news/2021-03-association-consumption-ultra-processed-foods-colorectal.
    html Note: This article aims to introduce the progress of medical and health research and is not a treatment plan recommendation.

    If you need guidance on treatment plans, please go to a regular hospital for treatment.

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