Why choose a microscope insoluble particle tester for drug particle detection? The reason is very simple

1μm-50μm particles in medicines are basically difficult to identify with the naked eye, but if they are directly used in clinics or directly into the market without testing, if they are used on patients, they will inevitably cause particles to accumulate in the body.
If it flows into the blood vessels, If a certain amount of particles are in the body, you will not feel any abnormality in the body, but once the amount exceeds a certain amount, it will likely cause blood vessel blockage.
Serious particles will also cause irritation and inflammation, resulting in the formation of granulomas
.

Therefore, we need to further emphasize that once the particles flow into the body, they cannot flow out of the body, and they will stay in the body for a long time and eventually affect the health of the body
.

The detection methods of the insoluble particle analyzer are divided into light resistance method and microscopic counting method.
The microscope method insoluble particle tester is a commonly used analysis, detection and release instrument for the verification department and various levels of drug testing in the injection drug research and development enterprises.
If you are confused, why not use a photoresist particle analyzer, let's discuss it in detail
.

First of all, we have to explain that for some preparations, the photoresist method can be used to test the insoluble particles, but some special intraocular injections cannot be tested by the photoresist method
.

The reason for using the micro-counting method for insoluble particles is that the speciality of intraocular injections makes it impossible to use the commonly used photoresist method to detect insoluble particles.
Because of the opacity and high viscosity of the sample itself, the photoresist method is used.
The test counts the sample itself and air bubbles as particles in the category of insoluble particles, which can give false results
.

In addition, the amount of the intraocular injection sample itself is too small to reach the lower limit of 200 microliters of samples detected by the photoresist method, which cannot be tested
.

The Chinese Pharmacopoeia stipulates that all injections should be checked for insoluble particles.
When the photoresist method does not meet the requirements or the test sample is not suitable for the photoresist method, the microscopic counting method should be used for the measurement, and the microscopic counting method should be used.
The determination result of the counting method is the final judgment basis, so the detection of insoluble particles by the microscope method is a very important choice
.