Why children are infected with new crowns with lighter symptoms New research reveals key benefits of immune response.

Since the outbreak of the new crown outbreak, it has been quickly discovered that children infected with the new coronavirus tend to have much lighter symptoms and lower mortality rates than adult patients.
study, published online in the scientific journal Science, scientists compared immune system responses shown by children and adults to new coronavirus infections to identify key differences.
findings will not only help to understand why new coronary symptoms are mild in children, but also be important for the development of vaccines and drugs to contain new crowns.
in the study, scientists at Yale University and the Albert Einstein College of Medicine examined blood and cell samples from patients of different ages, including 65 children and young people (under 24 years of age) and 60 adults.
after testing the types of immune cells in a patient's blood, antibody responses, and various cytokines produced by immune cells, the researchers found that two specific immune factors had higher levels of expression in children.
one of these is lecytocyte interleton 17a (IL-17a), a signaling molecule that helps mobilize the immune system to respond early in infection, and interferon γ (INF-γ), which fights virus replication.
analysis showed that the younger the patient, the higher the level of IL-17a γ inf-17a.
the body's immune response can be divided into congenital and adaptive immunity.
these two immune factors are part of the innate immune system and are characterized by a rapid response to various invading pathogens.
"Our findings suggest that children are more innogeneicly immune to the virus and can protect them from developing severe lung disease."
, one of the lead authors of the study, said.
, adults showed stronger adaptive immune system responses.
levels of meso-antibodies considered protective are significantly higher in adult patients, including severe adult patients requiring mechanical aeration.
" results suggest that more severe conditions occur in adults, not because adaptive immunity fails to cause T-cell or antibody responses.
" Professor Herold said, "Adult patients have too strong an adaptive immune response, which may promote related inflammation such as acute respiratory distress syndrome."
the findings, the researchers suggest that treatments that enhance congenital immune responses in the early stages of the disease may be more helpful.
Herold notes that most candidates for vaccines to prevent new coronary infections are designed to raise levels of meso-antibodies, and that "vaccines that improve immunity in other ways may also be considered, such as those that increase the innity immune response."
" References: immune Responses to SARS-CoV-2 Infect in Alyssa Pediatrics and Adult Patients. Science Translational Medicine. DOI: 10.1126 / scitranslmed.abd5487 . Retrieved Sep. 22, 2020, from.