Which of the various new formulations such as the new crown vaccine nasal spray will succeed?

Text | Little Pharmacist of Shanghai Beach

Recently, CanSino Bio (688185.

This nasal spray formulation can quickly achieve immune protection, shorten the vaccination cycle, and achieve herd immunity in the shortest time, and the virus can be stored between 2 to 8 degrees, which is particularly convenient for nasal spray preparations.

Figure 1 The recent market quotations of Cansino shares, first rose and then fell

Is subcutaneous injection the only way to vaccinate?

Under normal circumstances, many of us imagine that getting immunized is like getting a flu vaccine: we will go straight to hospitals at all levels, roll up our sleeves, feel a rapid tingling in our arms, and the new vaccination will be done.

However, everyone knows that the new coronavirus is transmitted through the respiratory tract.

Figure 2 Science reports that nasal medication can combat the new coronavirus

In addition to the nasal cavity of the vaccine, oral mucosal administration is also a new way

In theory, this site-specific strategy may provide stronger protection against COVID-19 coronavirus disease than vaccination, because it is closer to natural COVID-19 infection and is at the key position where the virus enters.

In addition, vaccine components that use bacteria as carriers can deliver antigens directly to the mucosal tissues of the nose and oral cavity.

The new crown vaccine is administered through the mucous membrane, which has obvious advantages

If the new crown vaccine uses mucosal administration, it must use viruses or bacteria as carriers.

summary

In short, due to the widespread spread of the global new crown virus, we can know that the new crown vaccine will not be the only one in the future, but will be in a state of contention.