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What is the risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus who smoke?

 Last Update: 2021-09-29
 Source: Internet
 Author: User

The 776 SLE patients in the exploratory cohort and the 836 SLE patients in the repeat cohort were genotyped using a 200K single nucleotide polymorphism (SNP) chip and a customized sequence
.

60 SNPs related to SLE were analyzed (p<5.

Conclusion: Smoking SLE patientswith STAT4 susceptibility alleles seem to increase the risk of myocardial infarction and nephritis .

Source:
Reid S, Hagberg N, Sandling JK, Alexsson A, Pucholt P, Sjöwall C, Lerang K, Jönsen A, Gunnarsson I, Syvänen AC, Troldborg AM, Voss A, Bengtsson AA, Molberg Ø, Jacobsen S, Svenungsson E, Rönnblom L , Leonard D.

Interaction between theSTAT4rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus.
Ann Rheum Dis.

Reid S, Hagberg N, Sandling JK, Alexsson A, Pucholt P, Sjöwall C, Lerang K, Jönsen A, Gunnarsson I, Syvänen AC, Troldborg AM, Voss A, Bengtsson AA, Molberg Ø, Jacobsen S, Svenungsson E, Rönnblom L , Leonard D.
Interaction between theSTAT4 Leave a message here

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What is the risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus who smoke?

The 776 SLE patients in the exploratory cohort and the 836 SLE patients in the repeat cohort were genotyped using a 200K single nucleotide polymorphism (SNP) chip and a customized sequence . 60 SNPs related to SLE were analyzed (p<5.

The 776 SLE patients in the exploratory cohort and the 836 SLE patients in the repeat cohort were genotyped using a 200K single nucleotide polymorphism (SNP) chip and a customized sequence
.

60 SNPs related to SLE were analyzed (p<5.