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What happens after changing the "sponge" of stem cell nuclei?

 Last Update: 2022-01-07
 Source: Internet
 Author: User

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The movement of a tiny, inert bead in the cell nucleus at different stages of the differentiation process

Source: Tokyo Metropolitan University

Researchers from Tokyo City University discovered how the sponginess and stickiness of stem cell nuclei control how they "differentiate" into specialized cells

Most of our understanding of biological materials and living systems is biochemical, the intricate pathways that connect a large number of complex chemical substances

The same principle applies not only to cells, but also to the substances that make up cells

As the cells differentiated and specialized, the research team found that the nucleus became less solid and more liquid-like

For a long time, people believed that the accumulation of chromatin was related to the suppression of certain genes

10.

Intranuclear mesoscale viscoelastic changes during osteoblastic differentiation of human mesenchymal stem cells

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