What does it mean to find a new strain of the corona virus in multiple countries?

Medicine Network, August 18th, as the global scientific community and the new crown virus race, new challenges are emerging.
recently, India, Malaysia, the Philippines and other countries have found a new crown virus variant strain, some of which spread 10 times faster than the general strain.
is it easy to mutate the new corona virus? What are the effects of mutations on virus transmission and vaccine development? With the news, the confusion of the people also arises.
need to know is that the virus is a very simple organism, usually consisting of only two substances: the protein shell (the shell) and the nucleic acid (DNA or RNA, the new crown virus is the latter).
it does not have an independent life system and can only survive in living cells.
when the new crown virus enters the cell for rapid replication, it means that the virus RNA replicates rapidly, which inevitably results in errors and is therefore prone to mutation.
constantly mutates to help the virus evade the identification of antibodies.
as part of the evolution of the virus, the new crown virus mutation is not a new topic in the scientific community.
take the four cases of D614G mutant strains found in Malaysia as an example, as early as early July, a study in the journal Cell discussed the D614G variant, a new coronary virus variant caused by amino acid changes.
studies have suggested that the 614th amino acid D, located in the new crown virus protrusion protein, has been turned into glycine (G), an amino acid change that is critical to the infectious nature of pathogens.
researchers tested the number of viruses in patients with new coronary pneumonia.
results show that the G strain produces more viruses in the human body than the D strain.
G strain did not lead to a higher hospitalization rate, indicating that it did not lead to more serious illness.
but carrying G amino acids is more contagious.
In response, Maria van Kohoff, technical director of the World Health Organization's Health Emergency Program, said at a press conference that in February, D614G mutations had appeared in early viral gene sequences found in Places such as Europe, and studies showed that 29 percent of new coronary virus samples showed the mutation, but there was no evidence that it would cause more serious illness.
On the effects of mutations on viral toxicity, researchers at Yale University and the University of Sydney have written in Nature Microbiology that mutations can increase or weaken viral toxicity, that virus toxicity and transmission are controlled by multiple genes, that multiple mutations are needed to evolve, and that the consequences of mutations require experimental and epidemiological evidence and should not be too alarming.
India has discovered two new viral linees and 73 new variants of the virus strain, the Press Trust of India reported.
number of new variants, there are inevitable concerns about its impact on the prevalence of the new corona virus.
This, Shanghai Communication Medical College, Shanghai Institute of Immunology Professor, Shanghai Institute of Immunology Vice President Wang Ying told the media that the mutation of the new crown virus may have a certain regional, the epidemic strains in different regions may have different mutations.
this is related to the genetic background of the species, and that new variants found in one region are less likely to be prevalent in another.
the virus itself, the biggest concern is whether the mutation will invalidate the vaccine that is being developed in a race against time.
, a professor at the U.S. Government, said the mutations are less likely to cause current vaccine development failures.
On the one hand, because there are enough sites in the new crown vaccine to produce immune protection, mutations in many gene sites do not necessarily invalidate the vaccine, on the other hand, vaccine developers should pay attention to the progress of the new crown virus mutation, explore the biological significance of these gene mutations, so as to more comprehensively grasp the design of candidate vaccines in vaccine development, to ensure that sufficient immune protection can be induced.
Chen Wei, a member of the Chinese Academy of Engineering and a researcher at the Institute of Military Medicine of the Academy of Military Sciences, also pointed out in an earlier interview that the new coronavirus mutation is fast, but also in the coronavirus category, the current rapid development of big data research, once there are new mutations, you can immediately find common target antigens, pathogenesis or receptors through bioinningation or big data mining, can quickly guide vaccine improvement.
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