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Pharmaceutical Network Technical Article : Bubble tablet press is an automatic rotating, continuous tablet machine, but also chemical, food, electronics and other industrial enterprises will be granulated raw materials pressed into tablets or punches of special equipment, suitable for small batch production At present, the market of the bubble tablet press can suppress a variety of shape, ring tablets, two-color tablets, and can suppress double-sided engraved with trademarks, text and simple graphics of tablets, equipped with overload protection devices, when the pressure overload, can automatically stop, this tablet press to improve the uniformity of tablet density, reduce the phenomenon of cracking, pine tablets
At present, the special tablet press is widely used in laboratories, hospitals, scientific research institutions and other places Industry said that the use of foam tablet press tablets, the material is selected reasonably, pressure made of tablets or punches to achieve satisfactory results In general, the selection of materials need to pay attention to the following several things
The material sizzling chip should have better liquidity and easily and evenly flow into the mold hole to fill a certain amount At the same time also need to have a certain degree of stickiness, so that the pressure can be pieced, but the industry also reminded that not too sticky, otherwise it is difficult to release
Auxiliary raw materials are mainly used as fillers, adhesives, moisturizers, lubricants and disintegrating agents in foaming sheets It is understood that some accessories often have several effects, such as starch can be used as fillers, bonding and disintegrating Therefore, users need to master the characteristics of various accessories, in the design of ingredients when reasonable application, not only can save the accessories, but also improve the quality of foam
Moisture absorption Of materials can not be ignored For example, the sugar powder is easy to absorb moisture, will make the made bubble flakes soft and moisture solution, the user should pay attention to
AdhesiveS The choice of adhesives has a great deal to do with the quality of the finished product If the viscosity is insufficient or the amount of use is too small, the pressed product is easy to loosen, crack, but the viscosity is too strong or too much, the particles will be too hard, the made bubble sugar is not easy to dissolve or disintegrate Syrup is a sticky adhesive that produces harder pieces of sugar
When choosing dextrin as the adhesive, it is understood that if the amount of dextrin is too large, the particles will be made too hard, the surface of the pressed sugar tablets often have spot, hemp dot, affecting the rate of sugar disintegrating
The industry said that the production is less individually used with dextrin, often with starch or sugar powder, etc in the appropriate ratio of combined use, or with starch applied to easy-to-loose bubble sugar
Acid-alkali material Acid-alkali material Acid-base material has a certain effect on the effect of foaming and production, the industry pointed out three points
First, the proportion of acid-alkali material sits on the foaming effect plays an important role, the general finished product carbon dioxide content is not less than 8%, in order to product sweet and moderate, to ensure that bicarbonate or carbonate in the role of complete, the amount of acid is generally slightly higher than the amount of alkali slightly higher
Second, if the formula must use citric acid, the production workshop humidity and temperature must be controlled within the recommended humidity temperature, otherwise it is difficult to do non-stick
Third, the citric acid is replaced with tartaric acid or rich maroacid, the effect is better without precipitation phenomenon Tartric acid instead of citric acid, moisture absorption will be greatly reduced, but the taste is not as good as using citric acid
Magnesium stearate Magnesium Steaurate has a certain effect on quality The industry said that magnesium stearate hydrophobic strong, excessive use will affect the sugar disintegrating or the production of cracking tablets
It is understood that in the process of using tablet press tablets is mostly the use of magnesium stearate as a lubricant, but do the dimensional C foam tabletall all raw materials and accessories should be soluble in water, because magnesium stearate is hydrophobic substances, insoluble in water, in the tablets using magnesium stearate will produce turbid precipitation phenomenon, it is recommended not to use or as little as possible.