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Chenruisheng biological research and development company to benirutotide; semeglutide; Liraglutide; Introduction to the research and development of tilbotide and other weight loss raw materials: semeglutide is a glucagon-like peptide receptor agonist, that is, GLP-1 receptor agonist, and the human body's GLP-1 is a peptide hormone
secreted by intestinal L cells.
Application: Semeglutide belongs to glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) class of hypoglycemic drugs, this drug increases insulin secretion in the form of glucose dependence, inhibits glucagon secretion, and can promote gastric emptying, central inhibition of appetite, reduce food intake, and then reduce glucose absorption to achieve the effect
of lowering blood sugar.
Mechanism of action: Its mechanism of action is to act on islet β cells, promote the synthesis and secretion of insulin, stimulate the value-added and differentiation of islet β cells, inhibit the apoptosis of islet β cells, increase the number of islet β cells, and have the effect of
protecting islet function.
It can also act on islet α cells, inhibit the release of glucagon, and reduce the release
of liver sugar.
Acts on islet δ cells, promotes the secretion of somatostatin, and participates in the inhibition of glucagon secretion
.
Enhance insulin sensitivity, slow down the emptying of the stomach, act on the hypothalamus to suppress appetite, reduce body weight, and achieve the effect
of lowering blood sugar through these effects.