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    Home > Active Ingredient News > Drugs Articles > Wary! Zhong Nanshan and other academicians remind: this winter's flu + new crown epidemic risk is extremely high! The death rate of double infection has increased sharply by 2.4 times!

    Wary! Zhong Nanshan and other academicians remind: this winter's flu + new crown epidemic risk is extremely high! The death rate of double infection has increased sharply by 2.4 times!

    • Last Update: 2022-11-14
    • Source: Internet
    • Author: User
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    Three academicians, Chinese disease control reminds: this winter's flu + new crown epidemic risk is extremely high! Please pay attention!

    Three academicians, Chinese disease control reminds: this winter's flu + new crown epidemic risk is extremely high! Please pay attention!

    Recently, at the "World Influenza Day" science popularization and academic conference on November 1, 2022, Zhong Nanshan, academician of the Chinese Academy of Engineering, made the latest research and judgment based on the situation of influenza at home and abroad, he pointed out: "The world is still facing the risk of superimposed epidemics of the new crown epidemic and influenza epidemics, especially this winter, and it is still necessary to strengthen research on scientific issues in strengthening influenza prevention and control
    .
    " ”

    Zhong Nanshan

    Subsequently, Gao Fu, an academician of the Chinese Academy of Sciences, also expressed his opinion, saying, "Since June this year, there has been a new round of avian influenza epidemic in Europe, and at the same time, there has been an unprecedented outbreak of H5N1 infection in poultry in the United States, which has a very high risk of spillover and infection of
    people.
    " Therefore, the superposition of influenza and new crown is a very big challenge
    we will face this winter and next spring.
    At present, the level of new crown vaccination is gradually increasing, but the influenza vaccination rate is generally low, which is a problem
    we need to pay attention to.

    Gao Fu

    Dong Chen, an academician of the Chinese Academy of Sciences, also said that at present, the world is still facing a high risk of superimposed epidemics of respiratory infectious diseases such as influenza and new crown pneumonia, and the prevention and control of respiratory infectious diseases has a long
    way to go.

    Dong Chen

    This is a flu warning made by several academicians and bigwigs to all walks of life, and on the same day, even the Chinese Center for Disease Control and Prevention issued "health tips on influenza prevention and control this autumn and winter"
    .

    According to the 35th week weekly report of the National Influenza Center in 2022, the proportion of influenza cases in northern provinces has been higher than the same period in 2019~2021 for 4 consecutive weeks, and the future situation is more critical
    .

    This year is indeed very different, with some troubling signals that we will face new threats
    this coming winter.

    In Australia, which is in the southern hemisphere, influenza has been the first to strike at the beginning of the year, reaching a five-year peak
    .
    In the northern hemisphere, where we live, some countries have also experienced more severe anti-seasonal summer flu epidemics
    .
    As of mid-June, the number of influenza-like cases reported this year in Guangzhou, China, has increased by 10.
    38 times
    compared to last year.

    Due to the implementation of COVID prevention and control measures, surveillance data over the past two years shows that influenza epidemic levels have been at a low level
    .
    But the situation is gradually changing
    .

    Zhang Wenqing, head of the World Health Organization's global influenza program, said, "At the beginning of the new crown epidemic, the epidemic situation of influenza was in a very weak state in the world, but the change occurred in the second half of 2021, and monitoring showed that the activity of influenza increased, whether located in the northern hemisphere or the southern hemisphere, many countries are like this, which indicates an important problem, that is, the next northern hemisphere flu season may also be like the southern hemisphere, there may be a seasonal peak of influenza affected by the new crown epidemic.
    "
    。 ”

    Zhang Wenqing

    According to the results of an 11-country modeling study released by The Lancet Global Health last month, the susceptibility of the current population to influenza has increased by up to 60% compared with before the new crown epidemic, and it is predicted that the peak amplitude of the influenza season in 2022 will increase by 1~5 times, and the epidemic scale will increase by up to 1~4 times
    .

    The Lancet Global Health

    This must be of great importance to
    us.

    But why is the risk of flu raids so high in various surveillance data?

    In this regard, Gao Fu said that one of the possible reasons is that in the past three years, the world has been in the implementation of public health interventions, the overall population immunity to influenza viruses is weak, and some countries have recently relaxed public health policies, in this case of re-exposure to the ubiquitous influenza virus, humans are easily infected
    .
    And the influenza virus has been mutating, and the influenza vaccination rate is low, which has caused the influenza
    virus to be more likely to circulate.

    Gao Fu

    Reminder again! Flu is not a common cold, please pay attention!!

    Reminder again! Flu is not a common cold, please pay attention!!

    The flu promotes new coronavirus infection and worsens symptoms

    The flu promotes new coronavirus infection and worsens symptoms

    New crown + influenza double infection, the mortality rate increased sharply by 2.
    4 times

    New crown + influenza double infection, the mortality rate increased sharply by 2.
    4 times

    There are always people who downplay the flu as a common cold, but it is by no means the case
    .

    Influenza can be considered a self-limited disease, for adults, the vast majority of people infected with influenza will not cause severe illness, about 1 week will heal itself, cough and other symptoms can last 1~2 weeks
    .

    However, for infants and young children, especially babies under the age of 2, it is more likely to develop severe cases, which will cause complications such as myocarditis, otitis media, and pneumonia, and parents need to be extremely vigilant
    .

    For the elderly and chronically ill elderly, they account for about 90% of influenza-related deaths and 50%~70%
    of hospitalizations.
    They are more likely to suffer long-term sequelae, including persistent loss of function and disability
    .

    The above is just the unilateral harm of the flu, if a person is infected with both the flu and the new crown, then what will happen?

    A new study published in The Lancet shows SARS-CoV-2 co-infection with influenza Viruses, respiratory syncytial virus, or adenoviruses answer this question for us
    .

    The Lancet

    The research team looked at data
    from more than 305,000 adults hospitalised in the UK between 6 February 2020 and 8 December 2021 due to the new coronavirus infection.

    6,965 of them were simultaneously detected with a respiratory virus
    during their coronavirus hospitalization.
    Of those, 227 were also infected with the flu virus, and these people experienced more severe symptoms
    .

    influenza virus

    Specifically, patients who were infected with the new coronavirus and co-infected with the influenza virus had a 4.
    14 times higher risk of developing ventilator treatment during their hospitalization than hospitalized patients who were only infected with the new coronavirus, and the risk of death increased sharply to 2.
    35 times
    .

    4.
    14 times 2.
    35 times

    This statistic clearly tells us that simultaneous infection with the new coronavirus and the influenza virus is a particularly dangerous situation
    .

    Sadly, many countries have begun to liberalize social distancing policies, which will lead to the simultaneous spread of COVID and influenza, increasing the chances of
    co-infection.
    Some experts suggest that the current testing strategy for new crown hospitalized patients should be changed now, and it is necessary to test new crown hospitalized patients for influenza testing for better treatment
    .

    In addition, we must also realize that the new crown + influenza double infection will play a synergistic role in causing disease, and the harm is even more terrible
    .

    According to a blockbuster study by Chinese scientists published in Cell, Coinfection with influenza A virus enhances SARS-CoV-2 infectivity shows that influenza virus infection can enhance the infectivity and pathogenicity
    of the new coronavirus.

    Cell influenza virus infection can enhance the infectivity and pathogenicity
    of the new coronavirus.

    Through experimental co-infection with influenza A virus (IAV) and pseudotype or active SARS-CoV-2 viruses, the study found that pre-infection of IAV significantly promotes SARS-CoV-2 infectivity
    in multiple cell types.

    In the study, the research team first applied the new crown pseudovirus and live virus to co-infection with influenza viruses (H1N1 type, H3N2 type, influenza B virus) respectively, and found that pre-infection with influenza virus will significantly promote the invasion and replication of the new crown virus, which exists in a variety of human respiratory cells and human lung tissue cells, and can also make the cells that are not infected with the new crown virus become completely susceptible cells, suggesting that the co-infection of the two viruses may cause more cells and tissues in the patient's body to be attacked by the virus

    The results of the study tell us that the co-infection of the two viruses is like adding fuel to the fire, making the new coronavirus more infectious and leading to more serious diseases, and the research provides a scientific basis
    for further attention to and prevention and control of the co-infection of the two viruses.

    What if the vaccination rate is too low?

    What if the vaccination rate is too low?

    Mabaloxavir may become a "flu fighter"!

    Mabaloxavir may become a "flu fighter"!

    The situation is so unoptimistic, but some people are still smiling and smiling, looking like they have nothing to do with me
    .

    Have we forgotten the saying that "a speck of dust from the times falls on each of us is a mountain"? The new crown is still tossing us, how can we stand idly by in the face of the risk of a high-risk flu raid this winter?

    Vaccination has always been the most effective way to prevent it, just look at our flu vaccination rates
    .

    Data show that the overall influenza vaccination rate in China is less than 5%, and the highest vaccination rate of preschool children is only about 12%.

    Among medical staff, a 2022 survey by scholars from Peking Union Medical College found that among 1,697 medical staff, the vaccination rate in the 2021/2022 influenza season was only 35.
    4%.

    Since last month, health departments in Beijing CDC, Shanghai CDC and other places have successively issued influenza vaccination reminders
    .
    According to Beijing Daily, the deadline for free influenza vaccination in Beijing is November 30, 2022, and self-funded influenza vaccination will continue until February
    2023.

    But as of late October, only 1.
    21 million people had been vaccinated against the flu, and Beijing had to have a permanent population of 20 million, which is why 1.
    21 million people had been vaccinated, and the vaccination rate had just reached 6%.

    121

    Oh my God, the free vaccine will give you a shot, you don't get it, which makes the author say that you are good
    .
    We always think that the flu is a small problem, no need to treat, this in the case of a single epidemic of influenza let's think so, but now is the time of the new crown pandemic, if you are infected with the flu, and infected with the new crown, do you think you can stand it?

    Talking about the vaccination of influenza vaccine, let's talk about drug treatment
    against influenza virus.

    Fortunately, we have anti-influenza drugs such as mabaloxavir, which can make us less nervous in the face of the flu
    .

    Mabaloxavir
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