Want to reduce hormones but afraid of relapse? Pay attention to these points and safely pass the critical period of hormone reduction

The culprit of the rebound of the disease

Lupus erythematosus is an autoimmune disease, glucocorticoids are still the preferred drug for the treatment of lupus erythematosus, it not only has anti-inflammatory effects, but also has immunosuppressive effects, can effectively control the disease
.
For hormones, I believe that many butterfly friends may already be very familiar with it, knowing that hormones are very important for inhibiting the condition of lupus, but there are also certain side effects, such as obesity, osteoporosis and so on
.
However, do butterfly friends know that in the process of hormone reduction, some improper operations can not only effectively help the hormone to reduce smoothly, but also may further aggravate the condition
.
The following error operations must be paid attention to:

Hormone tapering is too fast

Some patients due to the fear of hormone side effects, in the process of reduction did not follow the doctor's requirements, phased reduction, blind pursuit of speed, the final result: the amount of hormones did not decrease, but made the disease more serious
.

Hormones are used for too long

Because the condition is not controlled for a long time, large doses of hormones are used for a long time, and the inhibitory effect on the adrenal glands is becoming more and more obvious, and even causes the atrophy of the adrenal glands, resulting in the secretion function of the adrenal glands being inhibited and low, and the reduction should be more cautious
at this time.
The longer the time, the more difficult it is to reduce the amount, so don't rush
at this time.

It is related to whether or not to use drugs in combination

For some butterfly friends with mild disease, hormone therapy alone can achieve good results, and the dosage will not be too large under normal circumstances, and the probability of rebound at this time is relatively low
.
For some severely ill butterfly friends, because of their heart, liver, spleen, kidney has different degrees of damage, at this time simply with hormones not only the treatment effect is not good, the reduction is also very difficult, if combined with other immunosuppressant combination therapy, can appropriately reduce the use of hormones, after the condition is stable, it will also reduce the rebound
caused by hormone reduction.

Improper timing of reduction

If you choose to reduce the amount during the change of working environment, climate change, viral infection period, mild fever, conscious fatigue and other periods, even if the amount of reduction is very small, it will increase the recurrence rate of the disease
.

Any of the above inappropriate hormones may cause the disease to rebound
.
Although there may be some adverse reactions to reduce hormones, but reducing hormones is a major goal for us, how should butterfly friends safely pass the critical period of hormone reduction? Let's move on
.

Stop and reduce properly, in order to master the "destiny"

There is no fixed pattern of hormone reduction, which varies from person to person, so how to reduce hormones scientifically and reasonably is particularly important
.

Follow the stop reduction principle

In the above, we talked about hormone reduction should follow the principle of "rather slow than fast, rather less than more, and less and less", medium and large doses of corticosteroid therapy generally begin to be reduced after 6-8 weeks, up to 12 weeks
.
Clinically, according to the clinical symptoms and laboratory indicators of the acute phase of the patient: such as fever, proteinuria, erythrocyte sedimentation rate, thrombocytopenia and other basic control, the dose
can be appropriately reduced.
The larger dose can be reduced more, prednisone is taken more than 60mg per day, and the original dose is reduced by 10%
per week at the beginning of the reduction.

Watch closely for changes

When reducing the dose, it is necessary to pay close attention to the changes in the condition, and if there is a tendency to rebound, the dose should be increased immediately, and the daily increase is 5-10 mg
on the basis of the previous dose.
Long-term hormone butterfly friends, adrenal cortex function decrease, or even atrophy, the condition is easy to rebound after reduction, should be more cautious
.

Choose the right time

In the process of hormone reduction, as far as possible to eliminate the factors that cause recurrence, if there are large changes in the recent living or working environment, such as before enrollment, to work in a sun-exposed environment, before surgery, etc.
, or when there is often fever, fatigue, etc.
recently, we do not recommend hormone reduction
.

In addition, a stable living environment and maintaining a pleasant mood are also factors that
contribute to the success of the reduction.

In the process of treating SLE, whether the reduction of hormones is appropriate is the key to the success or failure of treatment, mutual aid Jun very well understands everyone's mood of wanting to reduce hormones as soon as possible, but they can't eat hot tofu in a hurry, and we must reduce hormones gradually
.
If you have uncomfortable symptoms due to hormone reduction, be sure to go to the hospital in time
.