U.S. uses genetically modified technology to cultivate anti-cancer laboratory mice
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Last Update: 2020-07-06
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Source: Internet
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Author: User
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a team at the University of Kentucky reports in the latest issue of the journal Cancer Research
they have successfully developed anti-cancer laboratoryby implanting aatumor,and hope to develop new ways to treat human cancer based on animal modelsA team led by University of Kentucky radiologist Vivek Reneka found atumorinhibitory gene called Par-4 in the prostate of laboratory miceThey foundthatthe gene kills cancer cells,without harming normal cellsThe "killer gene" that specifically targets cancer cells is rare, so the team believes Par-4 has great potential for cancer treatment They introduced the gene into the eggs of normal laboratory mice and implanted the genetically modified eggs into the surrogate mice As a result, the newborn mice had obvious immunity to cancer The newborn mice were able to grow normally without birth defects, and the mice lived for several months longer than normal mice in the control group, indicating that the added genes did not produce toxic side effects Radiation or chemotherapy currently used in human cancer treatment can damage the normal cells of cancer patients, resulting in varying degrees of toxic side effects In the future, it is possible to implant the Par-4 gene into the body through bone marrow transplants to fight various cancer cells, Reneka said But it will take time for this approach to be truly applied to human cancer treatment
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