U.S. researchers use genetic engineering to cure autism in laboratory mice
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Last Update: 2020-07-05
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Source: Internet
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Author: User
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U.Sresearchersthey have successfully eliminated theof a key symptom of an autism and mental retardeddiseasein laboratory mice,the results could help discover new treatments for human patientsMassachusetts Institute of Technology conducted the study on laboratory mice to treat "brittle X syndrome," Reuters reportedAbout 100,000 people in the U.
Sthedisease" Brittle X syndrome "is the most common genetic cause of autism and mental retardation
,caused by a gene deficiency called the "fragile X mental retardation protein." The defect is believed to block protein synthesis in the brainThe researchers tried to prove that the absence of the "brittle X-intellectual retardation protein" caused the gene m GluR5, which stimulates protein synthesis, to be uncontrolledGenetic engineering experiments have shown that reducing the number of m GluR5 in laboratory mice can help reduce the symptoms of abnormality caused by other important protein deficiencies, such as reducing the number of seizures Although the team used genetic engineering to reduce the number of m GluR5 in laboratory mice, the study offers hope for a drug to treat diseases in humans The drug will soon enter the experimental phase " Brittle X syndrome "is passed on to men the next generation through the mother's genes, with a one-in-four-thousandchance chance of being inherited People who are infected either have ADHD or are prone to autism The findings were published in the journal Neuron Tuesday,
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