U.S. researchers have found that pairing toxic proteins may cause BSE

Introduction: US researchers recently obtained the first images of the toxic protein related to mad cow disease, and found that the protein can be combined in a paired way, which may lead to human disease Virulent protein is a kind of human protein Scientists always think that it is usually a single molecule But in a joint study, researchers at the Cleveland medical center and the University of Casey reserve School of medicine in the United States found that two of the proteins were paired At present, many research groups in the world are studying the pathogenic mechanism of venom protein, in order to find out how normal and harmless venom protein can be transformed into the form leading to BSE The findings of the above scientists indicate that the pairing of virulent protein and virulent protein may be a transitional step in the above transformation process Scientists believe that this discovery reveals the other side of the toxic protein, which will help to develop technologies to test the pathogenesis of diseases related to toxic protein and develop drugs to prevent the formation of toxic protein pairing Researchers from the Cleveland medical center and the medical school of Casey Reserve University reported in the new issue of natural structural biology that they first transferred the human gene carrying the instruction of toxic protein synthesis into a bacterium, which generates toxic protein, and then crystallizes the toxic protein Then the researchers bombarded the crystal venom with X-ray, and recorded the reflected wave data after the ray met the electron cloud around the venom atom with computer Then the computer constructed the structure framework of the venom protein according to the data Scientists say they were lucky to get an image of a matching toxin (author:) share to feed Weibo share to: