Two Nat Foods: What's wrong with eating? The urine knows! New urine test test scan sie-healthy diet!

, June 28, 2020 /
PRNewswire/ -- Scientists have completed a massive five-minute urine test that measures a person's dietary health and produces a person's unique urine "fingerprints."scientists at Imperial College London, working with colleagues from Northwestern University, the University of Illinois and Murdoch University to analyze the levels of 46 so-called metabolites found in the urine of 1,848 people in the United States
the team published their findings in the journal Nature Food, which they say is considered an objective indicator of dietary quality and is produced when the body digests different foodsThe study was funded by the National Institutes of Health and the British Institute of Health Dataphoto source: Nature Foodstudy author Dr Joram Posma, from imperial college of technology's Department of Metabolism, Digestive and Reproductive Sciences, said: "Diet is a key factor in human health and disease, although it is notoriously difficult to measure because it depends on a person's ability to recall what they eat and how much they eatFor example, getting people to track their diet through apps or diaries often leads to inaccurate reports of what they actually eatThe study suggests that the technology could help provide in-depth information about a person's diet quality and whether it is suitable for their individual biological makeup"
study revealed a link between 46 metabolites in urine and the types of foods or nutrients in the dietFor example, some metabolites are associated with alcohol intake, while others are associated with the intake of citrus fruits, fructose, glucose and vitamin cThe team also found that metabolites in urine were associated with intake of red meat, other meats such as chicken, and nutrients such as calciumCertain metabolites are also associated with health conditions -- compounds such as metastases and sodium (indicators of salt intake) found in urine are also associated with obesity andhypertensionProfessor Paul Elliott, co-author of the study and head of the Department of Epidemiology and Public Health Medicine at Imperial College of Technology, said: "By carefully measuring people's diet and collecting urine over a 24-hour period, we can link our dietary intake with the output of urine metabolites, which can help improve our understanding of how diet affects health A healthy diet differs from those in the urine compared to those that lead to worse health outcomes "
in a second study by the same team of researchers, also published in Nature Food, the team developed a five-minute test using the technique, which showed that the mixture of metabolites in urine varied from person to person the team says the technique, which produces "fingerprints" of individual urine, allows people to get healthy eating advice tailored to their biological characteristics This is known as "precision nutrition" and can provide health professionals with more specific information about the quality of an individual's diet "Our technology provides key insights into how food is processed in different ways, and can help health professionals such as dietitians provide tailored dietary advice for each patient," explained Dr Isabel Garcia-Perez of imperial university's Department of Metabolism, Digestive and Reproductive Sciences, the study Dr Dr Garcia-Perez added that the team now plans to use this dietary analysis technique in people at risk of cardiovascular disease researchers say the urine "fingerprints" can be used to form a person's personal score -- known as dietary metabolic type score, or DMS in their experiment, the team asked 19 people to follow four different dietary habits -- from very healthy eating habits (following 100% of the World Health Organization's balanced diet recommendations) to unhealthy eating habits (following 25% who recommend the World Health Organization diet) team found that people who followed the same diet had different DMS scores Photo Source: Nature Food
The team's study also showed that the higher a person's DMS score, the healthier the diet The higher the DMS score, the lower the blood sugar and the more energy the body gets through the urine team found that the difference between high-energy urine (i.e., high DMS score) and low-energy urine (low DMS score) equates to people with high DMS scores losing four more calories a day or 1,500 calories a year This means a 215 grams of body fat difference each year, the team calculated next step is to study the relationship between a person's urine metabolite fingerprints and the risk of obesity, diabetes and high blood pressure Professor Gary Frost, co-author of the study and chairman of nutrition and dietatias at Imperial College, said: "These findings provide a new and deeper understanding of how our bodies process and use food at the molecular level The study raises the question of whether we should rewrite the table to include these new metabolites that have biological effects on the body Professor John Mathers, co-author of the study and director of the Centre for Human Nutrition Research at the University of Newcastle, said: "We show edited here how different people metabolize the same food in highly different ways This is instructive in understanding the development of nutrition-related diseases and providing more personalized dietary recommendations to improve public health " (BioValleyBioon.com) References: Urine test test sifs quality of your diet-andher it's the best fit for your body
Posma, J.M et al.
Nutriome-metabolome relationships for insights into dietary intake and Nat Food (2020) doi.org/10.1038/s43016-020-0093-y
Garcia-Perez, I., Posma, J.M., Chambers, E.S et al Dietary metabotype modelling predicts individual responses to dietary interventions.
Nat Food 1, 355-364 (2020) https://doi.org/10.1038/s43016-020-0092-z
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