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Twins study found that type 2 diabetes is linked to epigenetic changes

 Last Update: 2022-01-04
 Source: Internet
 Author: User

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Although identical twins have the same DNA, one of them may have type 2 diabetes, while the other will not

"Identical twins have the same genetic background, sex and age, so it is very interesting for researchers who are trying to understand the mechanism behind the disease

The study recruited 14 pairs of twins from Sweden and Denmark

Epigenetic changes occur through DNA methylation, a chemical process that controls gene function

The researchers’ analysis showed that in twins with type 2 diabetes, a gene responsible for the production of a specific microRNA (microRNA-30) is less active

Emma Nielsen said: "We were able to confirm our results in individuals without twin siblings, which proves that our results apply not only to identical twins, but to everyone

The researchers also conducted experiments.

The body's ability to process blood sugar in type 2 diabetic patients becomes worse

"We see the same pattern in patients with type 2 diabetes

Increasing understanding of the mechanisms behind this disease may lead to more effective treatments for type 2 diabetes

"Our research may be a step on the road of new treatment options, microRNA as an active substance for the treatment of patients with type 2 diabetes

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