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Today, with population growth, climate change, and other factors, food production has received unprecedented attenti. Recently, various studies on increasing grain production and the transformation of their achievements have been published one after anoth. However, some scientists have started "reverse thinking", that is, digging for treasures from food "wast. Because the part that is thrown away in food processing every year is also a huge resour. According to relevant data, in 2020, the global citrus production is about 140 million tons, but only about half is used for processing, and the remaining tens of millions of tons all go to the landfi. This "waste" can also have an impact on soil and aquatic systems if not handled proper. Therefore, if you can dig "treasure" in these food wastes, it will have a multi-pronged impa. So who can do this job? Of course, it is the "biochemical master" of intestinal bacteria!It is well known that the gut microbiota has a profound impact on the body, ranging from mental health to physical health, and it has been confirmed by more and more studi. In a study published in Cell on June 27, 2022, a research team led by Washington University in . Louis has identified a human gut bacterium that can "dig" out of orange waste and be "trapped" in Nutrients in Fib. The study highlights the relationship between microbiology, food science and nutrition, and establishes a method for using gut bacteria to "mine" natural products "trapped" by plant fiber, while simultaneously providing insights into the effects of dietary fiber on host physiolo. The mechanism of influence provides a new perspecti. In the new study, the researchers first fed mice colonized with human gut flora a high-fat, low-fiber diet supplemented with 10 percent or no fiber derived from orang. They then found that a molecule called N-methyl-5-hydroxytryptamine (N-Me-5HT) was released, and determined that it was a combination of human gut bacteria and orange fiber that released the compou. Relatively little is known about N-methyl-serotonin, but it is structurally very similar to serotonin (serotonin), a neurotransmitter that plays a role in mood, sleep, researchers s. and other key functions of the bo. The researchers then tested 49 different species of human gut bacteria and found that Bacteroides ovatus was effective at "digging" out N-Me-5HT from orange fibe. Molecular analysis revealed that Bacteroides ovale strains can release N-Me-5HT from fibers by expressing a pectin-degrading enzyme, which is lacking in the human genome and acts as a molecular scisso. Can break down the complex carbohydrate structure of N-Me-5HT "trapped" in orange fibe. The researchers also examined 133 edible plants, including staple food crops such as corn, wheat and rice, and found that N-Me-5HT is only present in a very small number of fiber types, including citrus fruits and peppercor. Next, they went on to analyze the biological effects of N-Me-5. When they fed germ-free mice a high-fat diet without orange fiber, supplementation with N-Me-5HT reduced fat storage, improved glucose metabolism in the liver, and produced faster intestinal transit tim. Finally, the team initially explored the translational potential of the above research in human tria. In a small clinical trial, researchers confirmed increased levels of N-Me-5HT in stool samples from participants who consumed a snack containing orange fib. This effect is fiber-specif. This effect did not occur when a snack containing pea fiber was ingest. Therefore, they concluded that orange fiber snacks specifically increased fecal N-Me-5HT content in a dose-dependent manner, and this content was correlated with the gene level of gut microbiota to digest pectinase "Serotonin is involved in many processes in the body, from mood to appetite to gut health, and we saw N-methyl-5 supplementation in mice," said study co-author . Michael Barratt, associate professor of pathology and immunolo. -Beneficial effects of seroton. Now, we are beginning to decipher the similarities and differences between N-methyl-5-hydroxytryptamine and seroton. "In conclusion, the new study suggests a number of potential approaches, including the addition of specific dietary fibe. Diet strate. "Ideally, we'd like to be able to recommend dietary fiber based on what we know about an individual's gut microbiome, especially those gut bacteria that have the ability to tap certain fiber metabolisms," said Barratt,correspondingauthor on the Edison Family Genom. Professor Jeffrey Gordon, Director of the Centre for Science and Systems Biology, added: "Different fibres have unique and rich repertoires of biomolecules, and each gut bacteria has a different ability to mine nutrients from a variety of fibres, including known Biomacromolecules and those that have yet to be discover. There is an infinite amount of space hidden he. Our research reveals the great potential of personalized nutriti. " Link to the paper: https://d. org/11016. ce. 2020004 Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Netwo. Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and te. Readers are only for reference and please Verify the relevant content yourse. Copyright Notice Some articles reproduced on this site are not original, and their copyright and responsibility belong to the original auth. All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and the source and author are clearly indicat. Media or individuals who do not wish to be reprinted can contact us for infringing information that can provide sufficient eviden. , bio149 will be deleted within 12 hours after confirmati. Users are welcome to submit original articles to 86371366@. com, which will be published on the homepage after review, and the copyright and responsibility of the articles belong to the send. |
Recently, various studies on increasing grain production and the transformation of their achievements have been published one after anoth.
However, some scientists have started "reverse thinking", that is, digging for treasures from food "wast.
Because the part that is thrown away in food processing every year is also a huge resour.
According to relevant data, in 2020, the global citrus production is about 140 million tons, but only about half is used for processing, and the remaining tens of millions of tons all go to the landfi.
This "waste" can also have an impact on soil and aquatic systems if not handled proper.
Therefore, if you can dig "treasure" in these food wastes, it will have a multi-pronged impa.
So who can do this job? Of course, it is the "biochemical master" of intestinal bacteria! It is well known that the gut microbiota has a profound impact on the body, ranging from mental health to physical health, and it has been confirmed by more and more studi.
In a study published in Cell on June 27, 2022, a research team led by Washington University in .
Louis has identified a human gut bacterium that can "dig" out of orange waste and be "trapped" in Nutrients in Fib.
The study highlights the relationship between microbiology, food science and nutrition, and establishes a method for using gut bacteria to "mine" natural products "trapped" by plant fiber, while simultaneously providing insights into the effects of dietary fiber on host physiolo.
The mechanism of influence provides a new perspecti.
In the new study, the researchers first fed mice colonized with human gut flora a high-fat, low-fiber diet supplemented with 10 percent or no fiber derived from orang.
They then found that a molecule called N-methyl-5-hydroxytryptamine (N-Me-5HT) was released, and determined that it was a combination of human gut bacteria and orange fiber that released the compou.
Relatively little is known about N-methyl-serotonin, but it is structurally very similar to serotonin (serotonin), a neurotransmitter that plays a role in mood, sleep, researchers s.
and other key functions of the bo.
The researchers then tested 49 different species of human gut bacteria and found that Bacteroides ovatus was effective at "digging" out N-Me-5HT from orange fibe.
Molecular analysis revealed that Bacteroides ovale strains can release N-Me-5HT from fibers by expressing a pectin-degrading enzyme, which is lacking in the human genome and acts as a molecular scisso.
Can break down the complex carbohydrate structure of N-Me-5HT "trapped" in orange fibe.
The researchers also examined 133 edible plants, including staple food crops such as corn, wheat and rice, and found that N-Me-5HT is only present in a very small number of fiber types, including citrus fruits and peppercor.
Next, they went on to analyze the biological effects of N-Me-5.
When they fed germ-free mice a high-fat diet without orange fiber, supplementation with N-Me-5HT reduced fat storage, improved glucose metabolism in the liver, and produced faster intestinal transit tim.
Finally, the team initially explored the translational potential of the above research in human tria.
In a small clinical trial, researchers confirmed increased levels of N-Me-5HT in stool samples from participants who consumed a snack containing orange fib.
This effect is fiber-specif.
This effect did not occur when a snack containing pea fiber was ingest.
Therefore, they concluded that orange fiber snacks specifically increased fecal N-Me-5HT content in a dose-dependent manner, and this content was correlated with the gene level of gut microbiota to digest pectinase
"Serotonin is involved in many processes in the body, from mood to appetite to gut health, and we saw N-methyl-5 supplementation in mice," said study co-author .
Michael Barratt, associate professor of pathology and immunolo.
-Beneficial effects of seroton.
Now, we are beginning to decipher the similarities and differences between N-methyl-5-hydroxytryptamine and seroton.
" In conclusion, the new study suggests a number of potential approaches, including the addition of specific dietary fibe.
Diet strate.
"Ideally, we'd like to be able to recommend dietary fiber based on what we know about an individual's gut microbiome, especially those gut bacteria that have the ability to tap certain fiber metabolisms," said Barratt,corresponding author on the Edison Family Genom.
Professor Jeffrey Gordon, Director of the Centre for Science and Systems Biology, added: "Different fibres have unique and rich repertoires of biomolecules, and each gut bacteria has a different ability to mine nutrients from a variety of fibres, including known Biomacromolecules and those that have yet to be discover.
There is an infinite amount of space hidden he.
Our research reveals the great potential of personalized nutriti.
" Link to the paper: https://d.
org/11016.
ce.
2020004
Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Netwo.
Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and te.
Readers are only for reference and please Verify the relevant content yourse.
Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and te.
Readers are only for reference and please Verify the relevant content yourse.
Copyright Notice
Some articles reproduced on this site are not original, and their copyright and responsibility belong to the original auth.
All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and the source and author are clearly indicat.
Media or individuals who do not wish to be reprinted can contact us for infringing information that can provide sufficient eviden.
, bio149 will be deleted within 12 hours after confirmati.
Users are welcome to submit original articles to 86371366@.
com, which will be published on the homepage after review, and the copyright and responsibility of the articles belong to the send.
Today, with population growth, climate change, and other factors, food production has received unprecedented attenti.All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and the source and author are clearly indicat.
Media or individuals who do not wish to be reprinted can contact us for infringing information that can provide sufficient eviden.
, bio149 will be deleted within 12 hours after confirmati.
Users are welcome to submit original articles to 86371366@.
com, which will be published on the homepage after review, and the copyright and responsibility of the articles belong to the send.
Recently, various studies on increasing grain production and the transformation of their achievements have been published one after anoth.
However, some scientists have started "reverse thinking", that is, digging for treasures from food "wast.
Because the part that is thrown away in food processing every year is also a huge resour.
According to relevant data, in 2020, the global citrus production is about 140 million tons, but only about half is used for processing, and the remaining tens of millions of tons all go to the landfi.
This "waste" can also have an impact on soil and aquatic systems if not handled proper.
Therefore, if you can dig "treasure" in these food wastes, it will have a multi-pronged impa.
So who can do this job? Of course, it is the "biochemical master" of intestinal bacteria! It is well known that the gut microbiota has a profound impact on the body, ranging from mental health to physical health, and it has been confirmed by more and more studi.
In a study published in Cell on June 27, 2022, a research team led by Washington University in .
Louis has identified a human gut bacterium that can "dig" out of orange waste and be "trapped" in Nutrients in Fib.
The study highlights the relationship between microbiology, food science and nutrition, and establishes a method for using gut bacteria to "mine" natural products "trapped" by plant fiber, while simultaneously providing insights into the effects of dietary fiber on host physiolo.
The mechanism of influence provides a new perspecti.
In the new study, the researchers first fed mice colonized with human gut flora a high-fat, low-fiber diet supplemented with 10 percent or no fiber derived from orang.
They then found that a molecule called N-methyl-5-hydroxytryptamine (N-Me-5HT) was released, and determined that it was a combination of human gut bacteria and orange fiber that released the compou.
Relatively little is known about N-methyl-serotonin, but it is structurally very similar to serotonin (serotonin), a neurotransmitter that plays a role in mood, sleep, researchers s.
and other key functions of the bo.
The researchers then tested 49 different species of human gut bacteria and found that Bacteroides ovatus was effective at "digging" out N-Me-5HT from orange fibe.
Molecular analysis revealed that Bacteroides ovale strains can release N-Me-5HT from fibers by expressing a pectin-degrading enzyme, which is lacking in the human genome and acts as a molecular scisso.
Can break down the complex carbohydrate structure of N-Me-5HT "trapped" in orange fibe.
The researchers also examined 133 edible plants, including staple food crops such as corn, wheat and rice, and found that N-Me-5HT is only present in a very small number of fiber types, including citrus fruits and peppercor.
Next, they went on to analyze the biological effects of N-Me-5.
When they fed germ-free mice a high-fat diet without orange fiber, supplementation with N-Me-5HT reduced fat storage, improved glucose metabolism in the liver, and produced faster intestinal transit tim.
Finally, the team initially explored the translational potential of the above research in human tria.
In a small clinical trial, researchers confirmed increased levels of N-Me-5HT in stool samples from participants who consumed a snack containing orange fib.
This effect is fiber-specif.
This effect did not occur when a snack containing pea fiber was ingest.
Therefore, they concluded that orange fiber snacks specifically increased fecal N-Me-5HT content in a dose-dependent manner, and this content was correlated with the gene level of gut microbiota to digest pectinase
"Serotonin is involved in many processes in the body, from mood to appetite to gut health, and we saw N-methyl-5 supplementation in mice," said study co-author .
Michael Barratt, associate professor of pathology and immunolo.
-Beneficial effects of seroton.
Now, we are beginning to decipher the similarities and differences between N-methyl-5-hydroxytryptamine and seroton.
" In conclusion, the new study suggests a number of potential approaches, including the addition of specific dietary fibe.
Diet strate.
"Ideally, we'd like to be able to recommend dietary fiber based on what we know about an individual's gut microbiome, especially those gut bacteria that have the ability to tap certain fiber metabolisms," said Barratt,corresponding author on the Edison Family Genom.
Professor Jeffrey Gordon, Director of the Centre for Science and Systems Biology, added: "Different fibres have unique and rich repertoires of biomolecules, and each gut bacteria has a different ability to mine nutrients from a variety of fibres, including known Biomacromolecules and those that have yet to be discover.
There is an infinite amount of space hidden he.
Our research reveals the great potential of personalized nutriti.
" Link to the paper: https://d.
org/11016.
ce.
2020004
Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Netwo.
Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and te.
Readers are only for reference and please Verify the relevant content yourse.
Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and te.
Readers are only for reference and please Verify the relevant content yourse.
Copyright Notice
Some articles reproduced on this site are not original, and their copyright and responsibility belong to the original auth.
All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and the source and author are clearly indicat.
Media or individuals who do not wish to be reprinted can contact us for infringing information that can provide sufficient eviden.
, bio149 will be deleted within 12 hours after confirmati.
Users are welcome to submit original articles to 86371366@.
com, which will be published on the homepage after review, and the copyright and responsibility of the articles belong to the send.
Bacteroides ovatus All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and the source and author are clearly indicat.
Media or individuals who do not wish to be reprinted can contact us for infringing information that can provide sufficient eviden.
, bio149 will be deleted within 12 hours after confirmati.
Users are welcome to submit original articles to 86371366@.
com, which will be published on the homepage after review, and the copyright and responsibility of the articles belong to the send.