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Tuberculous meningitis treatment

 Last Update: 2022-10-31
 Source: Internet
 Author: User

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Tuberculous meningitis is a disease
with a very high mortality and disability rate.
Early and targeted treatment can significantly improve prognosis
.
However, the principles of treatment for tuberculous meningitis are mostly derived from observational studies and clinical practice rather than well-designed controlled trials, so there is a lack of sufficient evidence
.
Early diagnosis is difficult, the presence of the blood-brain barrier and the prevalence of drug-resistant strains of tuberculosis make treatment more difficult
.
Here, we interpret the treatment options for tuberculous meningitis in the Fever Handbook, combined with multiple evidence-based evidence, and summarize the current treatment options for tuberculous meningitis
.

First, the choice of antituberculosis regimen for tuberculous meningitis

Antituberculosis drugs are selected in combination with blood-brain barrier permeability

Early use of fluoroquinolones (levofloxacin, gatifloxacin, ciprofloxacin) may be effective
.

2.
Treatment course of tuberculous meningitis

Third, the application of glucocorticoids in tuberculous meningitis

Fourth, the treatment plan for drug-resistant tuberculous meningitis

5.
Our research shows that linezolid can effectively treat severe tuberculous meningitis

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