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Traceless protein enzyme synthesis platform |
Obtaining and modifying proteins has always been one of the core issues in the field of life sciences.
There are two main methods: the first is to use the natural protein synthesis system (ribosome) in the organism to recombine and express proteins; the second is in recent years The vigorous development of artificial protein synthesis methods.
Zhong ASTRI ASTRI
The PALME platform consists of an upstream activation module and a downstream connection module
.
The platform has no specific restrictions on the substrate sequence, and can use solid-phase synthetic peptides, recombinantly expressed natural proteins, etc.
China Kexue Yuan senior LI Rui-feng Institute of Microbiology, co-author for the study of Zhu Tong PhD, and Dr.
Schmidt of Fresenius, Fresenius is Nuijens and Microbiology, Dr.
Wu edge researcher for the common Corresponding author
.
The completion of the work was also greatly assisted by researcher Fang Min and Yan Jinghua of the Institute of Microbiology
Academy of Sciences
Related paper information: https://doi.
https://doi.
org/10.
1093/nsr/nwab158