"Tianjin University - North China Pharmaceutical crystallization Engineering Laboratory"

On March 12, Professor Yin Qiuxiang, director of the national industrial crystallization engineering technology research center of Tianjin University, Professor Gong Junbo, deputy director, Professor Wang Yongli, and Liu Wenfu and Wei Qingjie, leaders of North China Pharmaceutical Co., Ltd., jointly unveiled the "Tianjin University North China Pharmaceutical crystallization engineering technology" Co., Ltd., which marks the national science and technology of Tianjin University The achievement of "particle process crystal product molecular assembly and shape optimization technology" of the invention award was really transformed in North China Pharmaceutical The cooperation between North China Pharmaceutical and Tianjin University began in the Seventh Five Year Plan period, with a profound historical origin In the cooperation, the two sides have won a number of national science and technology awards In the production of ceftriaxone sodium, ceftazidime, cefoxitin sodium and cefuroxime sodium raw materials crystallization and powder injection preparation, the "particle process crystal product molecular assembly and shape optimization technology" is used The structure of cephalosporins determines its poor temperature resistance, is very sensitive to acids and bases, resulting in poor product stability and easy degradation of substances harmful to the body By using solution crystallization, melt crystallization, reaction crystallization, salting out crystallization and other new coupling crystallization technologies, key technologies such as crystallization basic database, crystallization technology process package, computer-aided design software package and expert system of crystallization device are independently constructed, and finally product quality is improved The product stability and crystallization yield are improved The product yield is over 96%, and all technical and economic indexes are up to the domestic and international advanced level "Molecular assembly and morphology optimization technology of crystal products in particle process" won the second prize of national technological invention by national industrial crystallization engineering technology research center of Tianjin University At present, the technology has applied for four invention patents After the ceremony, the two sides discussed and exchanged views on new topics of in-depth cooperation and development This cooperation is in line with the overall requirements of the strategic cooperation of Beijing Tianjin Hebei integration It is a bold practice for the scientific research achievements of colleges and universities to promote the product technology of enterprises and enhance the core competitiveness of enterprises It provides a reference for the transformation of scientific research achievements of colleges and universities and the innovation of enterprise R & D mode Before the event, experts from the national industrial crystallization engineering technology research center of Tianjin University visited workshop 103, workshop 102, three-dimensional warehouse, laboratory of the quality department, R & D center and exhibition room of Huamin company, deeply praised the company's modern workshop and international first-class equipment, and also enhanced the confidence of cooperation between the two sides.