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This gene gives us a powerful brain!

 Last Update: 2022-09-20
 Source: Internet
 Author: User

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A chimpanzee brain organoid about 3 mm in size, brain stem cells are stained red; Brain stem cells expressing the ARHGAP11B gene appeared green

Image credit: Jan Fischer

ARHGAP11B, the complex name refers to a gene unique to humans that plays a vital role

The neocortex is the youngest part of the brain evolution and is home

Recent pioneering advances in pluripotent stem cell (PSC) research have provided a way out of this dilemma, leading to the development of

ARHGAP11B is the first human-specific gene

So, when the human-specific ARHGAP11B gene is expressed in the brain organoids of our closest chimpanzees, does it promote the proliferation and abundance of BPs? Conversely, is ARHGAP11B necessary to maintain complete levels of BP proliferation and abundance in human brain organoids? For research, the team introduced this gene, which is only present in humans, into lab-grown chimpanzee brain organoids

"These brain organoids allow us to study a core problem: ARHGAP11B

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