There is a difference between men and women in the new coronary pneumonia immune response

, Aug. 30 (Xinhua Zhang Mengran) An immunological study published in the British journal Nature on the 26th outlined the differences in immune responses between men and women with neo-coronary pneumonia. These findings may help guide the use of a gender-based approach to the treatment of male and female patients.
have shown that male patients are more severe than women, but the root cause of this difference is not clear. To gain insight into the problem, a team at Yale University School of Medicine assessed 98 patients diagnosed with mild to moderate neo-coronary pneumonia at Yale-New Blackrne Hospital in the United States, aged 18 or older, with an average age of 61 to 64.
team found that female patients produced a stronger and more sustained T-cell response than male patients. T-cells are an important part of the immune system and their role includes killing infected cells. Poor T-cell response in male patients was associated with poor disease outcomes.
compared to the healthy control group, patients with neocyto pneumonia had higher levels of innate immunocytokines and coercides (these signaling molecules were involved in raising immune cells to inflammatory sites). However, some of these factors have higher levels in male patients than in female patients. In female patients, higher levels of congenitic immunocytokines were associated with poor disease response.
results suggest that male patients may benefit from therapy that improves T-cell response, while female patients may benefit from therapy that inhibits early congenitic immune responses. Still, the researchers caution that they can't rule out other potential factors that could alter the risk of poor prognosticity in both male and female patients.