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The 2022 version of the tertiary public hospital assessment manual was released, which re-emphasized that the DDDs of antibiotics should be gradually reduced, which will further limit the use of antibiotics in tertiary hospitals
.
.
On April 2, the performance appraisal operation manual for tertiary public hospitals (version 2022) was released
.
Among them, among the three-level indicators of rational drug use, the requirements for the use of antibiotics (DDDs) are gradually reduced
.
.
Among them, among the three-level indicators of rational drug use, the requirements for the use of antibiotics (DDDs) are gradually reduced
.
This indicator refers to the average daily doses of antibiotics for adults (Defined Daily Doses, DDDs).
DDDs can reflect the medication dynamics and medication structure in different years.
The large DDDs of a certain antibiotic indicates that the frequency of medication is high and the medication intensity is high.
The choice of medicines tends to be high
.
DDDs can reflect the medication dynamics and medication structure in different years.
The large DDDs of a certain antibiotic indicates that the frequency of medication is high and the medication intensity is high.
The choice of medicines tends to be high
.
In fact, in past policies, the use of antimicrobials has been strictly regulated
.
This edition of the manual re-emphasizes the need to gradually reduce DDDs of antibiotics, which will further limit the use of antibiotics in tertiary hospitals
.
.
This edition of the manual re-emphasizes the need to gradually reduce DDDs of antibiotics, which will further limit the use of antibiotics in tertiary hospitals
.
The market size of antibacterial drugs has been greatly reduced, and the first five batches of countries have adopted 23 antibacterial drugs
From the perspective of market size, the market size of antibacterial drugs in China is shrinking significantly, especially in 2020, the downward trend is staggering.
Compared with 2019, the market size of antibacterial drugs in 2020 will decrease by about 16.
6 billion yuan, a year-on-year decrease of about 16.
6 billion yuan.
down 16.
44%
.
Compared with 2019, the market size of antibacterial drugs in 2020 will decrease by about 16.
6 billion yuan, a year-on-year decrease of about 16.
6 billion yuan.
down 16.
44%
.
With the continuous advancement of consistency evaluation and the normalization of centralized procurement, more and more antibacterial drugs will be included in centralized procurement
.
According to our statistics, 23 antibacterial drugs were included in the first five batches of national centralized procurement:
.
According to our statistics, 23 antibacterial drugs were included in the first five batches of national centralized procurement:
According to data from Minet.
com, under the further impact of centralized procurement and the epidemic, the terminal systemic use of antibacterial drugs in China's urban public hospitals, county-level public hospitals, urban community centers and township health centers (referred to as China's public medical institutions) fell sharply by 26.
45% in 2020.
%, sales exceeded 110 billion yuan; in the first half of 2021, its sales exceeded 58 billion yuan, a slight increase of 4.
03%
.
com, under the further impact of centralized procurement and the epidemic, the terminal systemic use of antibacterial drugs in China's urban public hospitals, county-level public hospitals, urban community centers and township health centers (referred to as China's public medical institutions) fell sharply by 26.
45% in 2020.
%, sales exceeded 110 billion yuan; in the first half of 2021, its sales exceeded 58 billion yuan, a slight increase of 4.
03%
.
Relevant policies are clear on the use of antibacterial drugs
Previously, the "Administrative Measures for Prescriptions" (Order No.
53 of the Ministry of Health of the People's Republic of China) and "Administrative Measures for the Clinical Application of Antibacterial Drugs" (Order No.
84 of the Ministry of Health) required medical institutions to carry out monitoring of the clinical application of antibacterial drugs.
The use of antibiotics in institutions and clinical professional departments shall be evaluated, and the appropriateness of the use of antibiotics shall be evaluated; the trend of antibiotic use shall be analyzed, and effective intervention measures shall be taken in time for the irrational use of antibiotics
.
53 of the Ministry of Health of the People's Republic of China) and "Administrative Measures for the Clinical Application of Antibacterial Drugs" (Order No.
84 of the Ministry of Health) required medical institutions to carry out monitoring of the clinical application of antibacterial drugs.
The use of antibiotics in institutions and clinical professional departments shall be evaluated, and the appropriateness of the use of antibiotics shall be evaluated; the trend of antibiotic use shall be analyzed, and effective intervention measures shall be taken in time for the irrational use of antibiotics
.
The "Notice on Printing and Distributing the Action Plan for Further Improvement of Medical Services" (Guo Wei Yi Fa [2015] No.
2) also requires the strengthening of rational drug use.
By the end of 2017, the use rate of antibiotics among inpatients in general hospitals should not exceed 60%, and the intensity of use of antibiotics should be controlled.
Below 40 DDDs per 100 people-days
.
2) also requires the strengthening of rational drug use.
By the end of 2017, the use rate of antibiotics among inpatients in general hospitals should not exceed 60%, and the intensity of use of antibiotics should be controlled.
Below 40 DDDs per 100 people-days
.
The "Notice on Further Strengthening the Management of Clinical Application of Antibacterial Drugs" ((Guowei Ban Yi Fa [2015] No.
42) stipulates that the intensity of antibiotic use in tertiary general hospitals should not exceed 40 DDDs, that in stomatological hospitals should not exceed 40 DDDs, and the intensity of antibacterial drugs should not exceed 40 DDDs.
No more than 30DDDs in hospitals, no more than 20DDDs in children's hospitals (calculated according to the prescribed daily dose standard for adults ), no more than 5DDDs in psychiatric hospitals, and no more than 40DDDs in maternity hospitals ( maternal and child health care centers)
.
42) stipulates that the intensity of antibiotic use in tertiary general hospitals should not exceed 40 DDDs, that in stomatological hospitals should not exceed 40 DDDs, and the intensity of antibacterial drugs should not exceed 40 DDDs.
No more than 30DDDs in hospitals, no more than 20DDDs in children's hospitals (calculated according to the prescribed daily dose standard for adults ), no more than 5DDDs in psychiatric hospitals, and no more than 40DDDs in maternity hospitals ( maternal and child health care centers)
.
The "Notice of the General Office of the National Health and Health Commission on Doing a Good Job in the Assessment of Rational Drug Use in Medical Institutions" (Guowei Ban Medical Letter [2019] No.
903) requires that the key content of the rational drug use assessment should include the use and management of antibiotics
.
903) requires that the key content of the rational drug use assessment should include the use and management of antibiotics
.
The "Notice of the National Health and Health Commission on Further Strengthening the Management of Antimicrobial Drugs to Curb Drug Resistance" (Guowei Medical Letter [2021373]) pointed out that local health administrative departments at all levels should include the rational use of antimicrobial drugs in hospital evaluation, public health Hospital performance assessment, rational drug use assessment and other work, and appropriately increase the assessment weight to play the role of the baton
.
.
The proportion of outpatient and inpatient use of antibacterial drugs has decreased significantly since the release of the National Action to Contain Bacterial Resistance
The abuse or irrational use of antibiotics has always been a problem that cannot be ignored
.
The National Health and Medical Commission previously pointed out that due to the widespread use of antibiotics, the global drug resistance situation is very serious.
It should be said that all bacteria have been found to be resistant, and bacteria that are completely sensitive to antibiotics are almost non-existent
.
.
The National Health and Medical Commission previously pointed out that due to the widespread use of antibiotics, the global drug resistance situation is very serious.
It should be said that all bacteria have been found to be resistant, and bacteria that are completely sensitive to antibiotics are almost non-existent
.
14 departments including the National Health and Medical Commission have jointly issued the "National Action Plan for Containment of Bacterial Resistance (2016-2020)", which proposes that by 2020, retail pharmacies will achieve full coverage of antibacterial drugs sold by prescription, and further restrict the sales of antibiotics at retail terminals
.
.
At present, domestic efforts to curb bacterial resistance have also achieved certain results
.
According to "The Paper", on November 18, 2021, the "Report on the Status of Antimicrobial Drug Management and Resistance in China (2021)" was released.
Lin Likai, Executive Deputy Director of Wuhan University Hospital Management Institute, said when interpreting the report, Judging from the overall drug resistance detection, Klebsiella pneumoniae, which we are very concerned about, has entered a state of no growth from 2020 to 2021, which is a very good phenomenon.
At the same time, the use of carbapenems has also been relatively good.
inhibition
.
Overall, the entire resistance evolution is moving in a positive direction
.
.
According to "The Paper", on November 18, 2021, the "Report on the Status of Antimicrobial Drug Management and Resistance in China (2021)" was released.
Lin Likai, Executive Deputy Director of Wuhan University Hospital Management Institute, said when interpreting the report, Judging from the overall drug resistance detection, Klebsiella pneumoniae, which we are very concerned about, has entered a state of no growth from 2020 to 2021, which is a very good phenomenon.
At the same time, the use of carbapenems has also been relatively good.
inhibition
.
Overall, the entire resistance evolution is moving in a positive direction
.
China has released the National Action Plan for Containment of Bacterial Resistance since 2016, and 2021 will be the fifth year of the implementation of the National Action Plan, and the implementation of the next five-year plan will soon begin
.
Lin Likai said that since the release of the national action plan, the proportion of outpatient use of antibiotics has dropped sharply, and the use of inpatient antibiotics has also undergone great changes and changes, especially in the application of surgical prevention, which has dropped a lot
.
.
Lin Likai said that since the release of the national action plan, the proportion of outpatient use of antibiotics has dropped sharply, and the use of inpatient antibiotics has also undergone great changes and changes, especially in the application of surgical prevention, which has dropped a lot
.
Lin Likai introduced that in the national action plan, China has always emphasized the protection of the effectiveness of treatment after infection, and has done a lot of work on this, including the research and development of new antibacterial drugs, especially the research on the mechanism of resistance, and the research on resistance Development of bacterial vaccines
.
.
In terms of new drug research and development, 7 new antibacterial drugs have been newly launched in the past five years, including 3 antibacterial drugs of class 1.
1, nanofloxacin malate, carrimycin and contezolid
.
In addition, the research and development of the Staphylococcus aureus vaccine has now entered the phase III clinical trial stage
.
1, nanofloxacin malate, carrimycin and contezolid
.
In addition, the research and development of the Staphylococcus aureus vaccine has now entered the phase III clinical trial stage
.
To sum up, since the national "antibacterial restriction order", the sales growth rate of antibacterial drugs in the hospital market has gradually slowed down.
Against the background of the assessment weight of the 2019-09-19, the future antimicrobial drug market will be subject to stricter restrictions, sales will continue to decline, and antimicrobial drug manufacturers will be greatly affected
.
Against the background of the assessment weight of the 2019-09-19, the future antimicrobial drug market will be subject to stricter restrictions, sales will continue to decline, and antimicrobial drug manufacturers will be greatly affected
.
The 2022 version of the tertiary public hospital assessment manual was released, which re-emphasized that the DDDs of antibiotics should be gradually reduced, which will further limit the use of antibiotics in tertiary hospitals
.
.
On April 2, the performance appraisal operation manual for tertiary public hospitals (version 2022) was released
.
Among them, among the three-level indicators of rational drug use, the requirements for the use of antibiotics (DDDs) are gradually reduced
.
.
Among them, among the three-level indicators of rational drug use, the requirements for the use of antibiotics (DDDs) are gradually reduced
.
This indicator refers to the average daily doses of antibiotics for adults (Defined Daily Doses, DDDs).
DDDs can reflect the medication dynamics and medication structure in different years.
The large DDDs of a certain antibiotic indicates that the frequency of medication is high and the medication intensity is high.
The choice of medicines tends to be high
.
DDDs can reflect the medication dynamics and medication structure in different years.
The large DDDs of a certain antibiotic indicates that the frequency of medication is high and the medication intensity is high.
The choice of medicines tends to be high
.
In fact, in past policies, the use of antimicrobials has been strictly regulated
.
This edition of the manual re-emphasizes the need to gradually reduce DDDs of antibiotics, which will further limit the use of antibiotics in tertiary hospitals
.
.
This edition of the manual re-emphasizes the need to gradually reduce DDDs of antibiotics, which will further limit the use of antibiotics in tertiary hospitals
.
The market size of antibacterial drugs has been greatly reduced, and the first five batches of countries have adopted 23 antibacterial drugs
From the perspective of market size, the market size of antibacterial drugs in China is shrinking significantly, especially in 2020, the downward trend is staggering.
Compared with 2019, the market size of antibacterial drugs in 2020 will decrease by about 16.
6 billion yuan, a year-on-year decrease of about 16.
6 billion yuan.
down 16.
44%
.
Compared with 2019, the market size of antibacterial drugs in 2020 will decrease by about 16.
6 billion yuan, a year-on-year decrease of about 16.
6 billion yuan.
down 16.
44%
.
With the continuous advancement of consistency evaluation and the normalization of centralized procurement, more and more antibacterial drugs will be included in centralized procurement
.
According to our statistics, 23 antibacterial drugs were included in the first five batches of national centralized procurement:
.
According to our statistics, 23 antibacterial drugs were included in the first five batches of national centralized procurement:
According to data from Minet.
com, under the further impact of centralized procurement and the epidemic, the terminal systemic use of antibacterial drugs in China's urban public hospitals, county-level public hospitals, urban community centers and township health centers (referred to as China's public medical institutions) fell sharply by 26.
45% in 2020.
%, sales exceeded 110 billion yuan; in the first half of 2021, its sales exceeded 58 billion yuan, a slight increase of 4.
03%
.
com, under the further impact of centralized procurement and the epidemic, the terminal systemic use of antibacterial drugs in China's urban public hospitals, county-level public hospitals, urban community centers and township health centers (referred to as China's public medical institutions) fell sharply by 26.
45% in 2020.
%, sales exceeded 110 billion yuan; in the first half of 2021, its sales exceeded 58 billion yuan, a slight increase of 4.
03%
.
Relevant policies are clear on the use of antibacterial drugs
Previously, the "Administrative Measures for Prescriptions" (Order No.
53 of the Ministry of Health of the People's Republic of China) and "Administrative Measures for the Clinical Application of Antibacterial Drugs" (Order No.
84 of the Ministry of Health) required medical institutions to carry out monitoring of the clinical application of antibacterial drugs.
The use of antibiotics in institutions and clinical professional departments shall be evaluated, and the appropriateness of the use of antibiotics shall be evaluated; the trend of antibiotic use shall be analyzed, and effective intervention measures shall be taken in time for the irrational use of antibiotics
.
53 of the Ministry of Health of the People's Republic of China) and "Administrative Measures for the Clinical Application of Antibacterial Drugs" (Order No.
84 of the Ministry of Health) required medical institutions to carry out monitoring of the clinical application of antibacterial drugs.
The use of antibiotics in institutions and clinical professional departments shall be evaluated, and the appropriateness of the use of antibiotics shall be evaluated; the trend of antibiotic use shall be analyzed, and effective intervention measures shall be taken in time for the irrational use of antibiotics
.
The "Notice on Printing and Distributing the Action Plan for Further Improvement of Medical Services" (Guo Wei Yi Fa [2015] No.
2) also requires the strengthening of rational drug use.
By the end of 2017, the use rate of antibiotics among inpatients in general hospitals should not exceed 60%, and the intensity of use of antibiotics should be controlled.
Below 40 DDDs per 100 people-days
.
2) also requires the strengthening of rational drug use.
By the end of 2017, the use rate of antibiotics among inpatients in general hospitals should not exceed 60%, and the intensity of use of antibiotics should be controlled.
Below 40 DDDs per 100 people-days
.
The "Notice on Further Strengthening the Management of Clinical Application of Antibacterial Drugs" ((Guowei Ban Yi Fa [2015] No.
42) stipulates that the intensity of antibiotic use in tertiary general hospitals should not exceed 40 DDDs, that in stomatological hospitals should not exceed 40 DDDs, and the intensity of antibacterial drugs should not exceed 40 DDDs.
No more than 30DDDs in hospitals, no more than 20DDDs in children's hospitals (calculated according to the prescribed daily dose standard for adults ), no more than 5DDDs in psychiatric hospitals, and no more than 40DDDs in maternity hospitals ( maternal and child health care centers)
.
42) stipulates that the intensity of antibiotic use in tertiary general hospitals should not exceed 40 DDDs, that in stomatological hospitals should not exceed 40 DDDs, and the intensity of antibacterial drugs should not exceed 40 DDDs.
No more than 30DDDs in hospitals, no more than 20DDDs in children's hospitals (calculated according to the prescribed daily dose standard for adults ), no more than 5DDDs in psychiatric hospitals, and no more than 40DDDs in maternity hospitals ( maternal and child health care centers)
.
The "Notice of the General Office of the National Health and Health Commission on Doing a Good Job in the Assessment of Rational Drug Use in Medical Institutions" (Guowei Ban Medical Letter [2019] No.
903) requires that the key content of the rational drug use assessment should include the use and management of antibiotics
.
903) requires that the key content of the rational drug use assessment should include the use and management of antibiotics
.
The "Notice of the National Health and Health Commission on Further Strengthening the Management of Antimicrobial Drugs to Curb Drug Resistance" (Guowei Medical Letter [2021373]) pointed out that local health administrative departments at all levels should include the rational use of antimicrobial drugs in hospital evaluation, public health Hospital performance assessment, rational drug use assessment and other work, and appropriately increase the assessment weight to play the role of the baton
.
.
The proportion of outpatient and inpatient use of antibacterial drugs has decreased significantly since the release of the National Action to Contain Bacterial Resistance
The abuse or irrational use of antibiotics has always been a problem that cannot be ignored
.
The National Health and Medical Commission previously pointed out that due to the widespread use of antibiotics, the global drug resistance situation is very serious.
It should be said that all bacteria have been found to be resistant, and bacteria that are completely sensitive to antibiotics are almost non-existent
.
.
The National Health and Medical Commission previously pointed out that due to the widespread use of antibiotics, the global drug resistance situation is very serious.
It should be said that all bacteria have been found to be resistant, and bacteria that are completely sensitive to antibiotics are almost non-existent
.
14 departments including the National Health and Medical Commission have jointly issued the "National Action Plan for Containment of Bacterial Resistance (2016-2020)", which proposes that by 2020, retail pharmacies will achieve full coverage of antibacterial drugs sold by prescription, and further restrict the sales of antibiotics at retail terminals
.
.
At present, domestic efforts to curb bacterial resistance have also achieved certain results
.
According to "The Paper", on November 18, 2021, the "Report on the Status of Antimicrobial Drug Management and Resistance in China (2021)" was released.
Lin Likai, Executive Deputy Director of Wuhan University Hospital Management Institute, said when interpreting the report, Judging from the overall drug resistance detection, Klebsiella pneumoniae, which we are very concerned about, has entered a state of no growth from 2020 to 2021, which is a very good phenomenon.
At the same time, the use of carbapenems has also been relatively good.
inhibition
.
Overall, the entire resistance evolution is moving in a positive direction
.
.
According to "The Paper", on November 18, 2021, the "Report on the Status of Antimicrobial Drug Management and Resistance in China (2021)" was released.
Lin Likai, Executive Deputy Director of Wuhan University Hospital Management Institute, said when interpreting the report, Judging from the overall drug resistance detection, Klebsiella pneumoniae, which we are very concerned about, has entered a state of no growth from 2020 to 2021, which is a very good phenomenon.
At the same time, the use of carbapenems has also been relatively good.
inhibition
.
Overall, the entire resistance evolution is moving in a positive direction
.
China has released the National Action Plan for Containment of Bacterial Resistance since 2016, and 2021 will be the fifth year of the implementation of the National Action Plan, and the implementation of the next five-year plan will soon begin
.
Lin Likai said that since the release of the national action plan, the proportion of outpatient use of antibiotics has dropped sharply, and the use of inpatient antibiotics has also undergone great changes and changes, especially in the application of surgical prevention, which has dropped a lot
.
.
Lin Likai said that since the release of the national action plan, the proportion of outpatient use of antibiotics has dropped sharply, and the use of inpatient antibiotics has also undergone great changes and changes, especially in the application of surgical prevention, which has dropped a lot
.
Lin Likai introduced that in the national action plan, China has always emphasized the protection of the effectiveness of treatment after infection, and has done a lot of work on this, including the research and development of new antibacterial drugs, especially the research on the mechanism of resistance, and the research on resistance Development of bacterial vaccines
.
.
In terms of new drug research and development, 7 new antibacterial drugs have been newly launched in the past five years, including 3 antibacterial drugs of class 1.
1, nanofloxacin malate, carrimycin and contezolid
.
In addition, the research and development of the Staphylococcus aureus vaccine has now entered the phase III clinical trial stage
.
1, nanofloxacin malate, carrimycin and contezolid
.
In addition, the research and development of the Staphylococcus aureus vaccine has now entered the phase III clinical trial stage
.
To sum up, since the national "antibacterial restriction order", the sales growth rate of antibacterial drugs in the hospital market has gradually slowed down.
Against the background of the assessment weight of the 2019-09-19, the future antimicrobial drug market will be subject to stricter restrictions, sales will continue to decline, and antimicrobial drug manufacturers will be greatly affected
.
Against the background of the assessment weight of the 2019-09-19, the future antimicrobial drug market will be subject to stricter restrictions, sales will continue to decline, and antimicrobial drug manufacturers will be greatly affected
.
The 2022 version of the tertiary public hospital assessment manual was released, which re-emphasized that the DDDs of antibiotics should be gradually reduced, which will further limit the use of antibiotics in tertiary hospitals
.
.
On April 2, the performance appraisal operation manual for tertiary public hospitals (version 2022) was released
.
Among them, among the three-level indicators of rational drug use, the requirements for the use of antibiotics (DDDs) are gradually reduced
.
.
Among them, among the three-level indicators of rational drug use, the requirements for the use of antibiotics (DDDs) are gradually reduced
.
This indicator refers to the average daily doses of antibiotics for adults (Defined Daily Doses, DDDs).
DDDs can reflect the medication dynamics and medication structure in different years.
The large DDDs of a certain antibiotic indicates that the frequency of medication is high and the medication intensity is high.
The choice of medicines tends to be high
.
DDDs can reflect the medication dynamics and medication structure in different years.
The large DDDs of a certain antibiotic indicates that the frequency of medication is high and the medication intensity is high.
The choice of medicines tends to be high
.
In fact, in past policies, the use of antimicrobials has been strictly regulated
.
This edition of the manual re-emphasizes the need to gradually reduce DDDs of antibiotics, which will further limit the use of antibiotics in tertiary hospitals
.
.
This edition of the manual re-emphasizes the need to gradually reduce DDDs of antibiotics, which will further limit the use of antibiotics in tertiary hospitals
.
The market size of antibacterial drugs has been greatly reduced, and the first five batches of countries have adopted 23 antibacterial drugs
The market size of antibacterial drugs has been greatly reduced, and the first five batches of countries have adopted 23 antibacterial drugs From the perspective of market size, the market size of antibacterial drugs in China is shrinking significantly, especially in 2020, the downward trend is staggering.
Compared with 2019, the market size of antibacterial drugs in 2020 will decrease by about 16.
6 billion yuan, a year-on-year decrease of about 16.
6 billion yuan.
down 16.
44%
.
Compared with 2019, the market size of antibacterial drugs in 2020 will decrease by about 16.
6 billion yuan, a year-on-year decrease of about 16.
6 billion yuan.
down 16.
44%
.
With the continuous advancement of consistency evaluation and the normalization of centralized procurement, more and more antibacterial drugs will be included in centralized procurement
.
According to our statistics, 23 antibacterial drugs were included in the first five batches of national centralized procurement:
.
According to our statistics, 23 antibacterial drugs were included in the first five batches of national centralized procurement:
According to data from Minet.
com, under the further impact of centralized procurement and the epidemic, the terminal systemic use of antibacterial drugs in China's urban public hospitals, county-level public hospitals, urban community centers and township health centers (referred to as China's public medical institutions) fell sharply by 26.
45% in 2020.
%, sales exceeded 110 billion yuan; in the first half of 2021, its sales exceeded 58 billion yuan, a slight increase of 4.
03%
.
com, under the further impact of centralized procurement and the epidemic, the terminal systemic use of antibacterial drugs in China's urban public hospitals, county-level public hospitals, urban community centers and township health centers (referred to as China's public medical institutions) fell sharply by 26.
45% in 2020.
%, sales exceeded 110 billion yuan; in the first half of 2021, its sales exceeded 58 billion yuan, a slight increase of 4.
03%
.
Relevant policies are clear on the use of antibacterial drugs
Relevant policies are clear on the use of antibacterial drugs Previously, the "Administrative Measures for Prescriptions" (Order No.
53 of the Ministry of Health of the People's Republic of China) and "Administrative Measures for the Clinical Application of Antibacterial Drugs" (Order No.
84 of the Ministry of Health) required medical institutions to carry out monitoring of the clinical application of antibacterial drugs.
The use of antibiotics in institutions and clinical professional departments shall be evaluated, and the appropriateness of the use of antibiotics shall be evaluated; the trend of antibiotic use shall be analyzed, and effective intervention measures shall be taken in time for the irrational use of antibiotics
.
53 of the Ministry of Health of the People's Republic of China) and "Administrative Measures for the Clinical Application of Antibacterial Drugs" (Order No.
84 of the Ministry of Health) required medical institutions to carry out monitoring of the clinical application of antibacterial drugs.
The use of antibiotics in institutions and clinical professional departments shall be evaluated, and the appropriateness of the use of antibiotics shall be evaluated; the trend of antibiotic use shall be analyzed, and effective intervention measures shall be taken in time for the irrational use of antibiotics
.
The "Notice on Printing and Distributing the Action Plan for Further Improvement of Medical Services" (Guo Wei Yi Fa [2015] No.
2) also requires the strengthening of rational drug use.
By the end of 2017, the use rate of antibiotics among inpatients in general hospitals should not exceed 60%, and the intensity of use of antibiotics should be controlled.
Below 40 DDDs per 100 people-days
.
2) also requires the strengthening of rational drug use.
By the end of 2017, the use rate of antibiotics among inpatients in general hospitals should not exceed 60%, and the intensity of use of antibiotics should be controlled.
Below 40 DDDs per 100 people-days
.
The "Notice on Further Strengthening the Management of Clinical Application of Antibacterial Drugs" ((Guowei Ban Yi Fa [2015] No.
42) stipulates that the intensity of antibiotic use in tertiary general hospitals should not exceed 40 DDDs, that in stomatological hospitals should not exceed 40 DDDs, and the intensity of antibacterial drugs should not exceed 40 DDDs.
No more than 30DDDs in hospitals, no more than 20DDDs in children's hospitals (calculated according to the prescribed daily dose standard for adults ), no more than 5DDDs in psychiatric hospitals, and no more than 40DDDs in maternity hospitals ( maternal and child health care centers)
.
standard standard health care __42) stipulates that the intensity of antibiotic use in tertiary general hospitals should not exceed 40 DDDs, that in stomatological hospitals should not exceed 40 DDDs, and the intensity of antibacterial drugs should not exceed 40 DDDs.
No more than 30DDDs in hospitals, no more than 20DDDs in children's hospitals (calculated according to the prescribed daily dose standard for adults ), no more than 5DDDs in psychiatric hospitals, and no more than 40DDDs in maternity hospitals ( maternal and child health care centers)
.
The "Notice of the General Office of the National Health and Health Commission on Doing a Good Job in the Assessment of Rational Drug Use in Medical Institutions" (Guowei Ban Medical Letter [2019] No.
903) requires that the key content of the rational drug use assessment should include the use and management of antibiotics
.
healthy healthy healthy903) requires that the key content of the rational drug use assessment should include the use and management of antibiotics
.
The "Notice of the National Health and Health Commission on Further Strengthening the Management of Antimicrobial Drugs to Curb Drug Resistance" (Guowei Medical Letter [2021373]) pointed out that local health administrative departments at all levels should include the rational use of antimicrobial drugs in hospital evaluation, public health Hospital performance assessment, rational drug use assessment and other work, and appropriately increase the assessment weight to play the role of the baton
.
.
The proportion of outpatient and inpatient use of antibacterial drugs has decreased significantly since the release of the National Action to Contain Bacterial Resistance
The abuse or irrational use of antibiotics has always been a problem that cannot be ignored
.
The National Health and Medical Commission previously pointed out that due to the widespread use of antibiotics, the global drug resistance situation is very serious.
It should be said that all bacteria have been found to be resistant, and bacteria that are completely sensitive to antibiotics are almost non-existent
.
.
The National Health and Medical Commission previously pointed out that due to the widespread use of antibiotics, the global drug resistance situation is very serious.
It should be said that all bacteria have been found to be resistant, and bacteria that are completely sensitive to antibiotics are almost non-existent
.
14 departments including the National Health and Medical Commission have jointly issued the "National Action Plan for Containment of Bacterial Resistance (2016-2020)", which proposes that by 2020, retail pharmacies will achieve full coverage of antibacterial drugs sold by prescription, and further restrict the sales of antibiotics at retail terminals
.
pharmacy pharmacy pharmacy.
At present, domestic efforts to curb bacterial resistance have also achieved certain results
.
According to "The Paper", on November 18, 2021, the "Report on the Status of Antimicrobial Drug Management and Resistance in China (2021)" was released.
Lin Likai, Executive Deputy Director of Wuhan University Hospital Management Institute, said when interpreting the report, Judging from the overall drug resistance detection, Klebsiella pneumoniae, which we are very concerned about, has entered a state of no growth from 2020 to 2021, which is a very good phenomenon.
At the same time, the use of carbapenems has also been relatively good.
inhibition
.
Overall, the entire resistance evolution is moving in a positive direction
.
.
According to "The Paper", on November 18, 2021, the "Report on the Status of Antimicrobial Drug Management and Resistance in China (2021)" was released.
Lin Likai, Executive Deputy Director of Wuhan University Hospital Management Institute, said when interpreting the report, Judging from the overall drug resistance detection, Klebsiella pneumoniae, which we are very concerned about, has entered a state of no growth from 2020 to 2021, which is a very good phenomenon.
At the same time, the use of carbapenems has also been relatively good.
inhibition
.
Overall, the entire resistance evolution is moving in a positive direction
.
China has released the National Action Plan for Containment of Bacterial Resistance since 2016, and 2021 will be the fifth year of the implementation of the National Action Plan, and the implementation of the next five-year plan will soon begin
.
Lin Likai said that since the release of the national action plan, the proportion of outpatient use of antibiotics has dropped sharply, and the use of inpatient antibiotics has also undergone great changes and changes, especially in the application of surgical prevention, which has dropped a lot
.
.
Lin Likai said that since the release of the national action plan, the proportion of outpatient use of antibiotics has dropped sharply, and the use of inpatient antibiotics has also undergone great changes and changes, especially in the application of surgical prevention, which has dropped a lot
.
Lin Likai introduced that in the national action plan, China has always emphasized the protection of the effectiveness of treatment after infection, and has done a lot of work on this, including the research and development of new antibacterial drugs, especially the research on the mechanism of resistance, and the research on resistance Development of bacterial vaccines
.
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In terms of new drug research and development, 7 new antibacterial drugs have been newly launched in the past five years, including 3 antibacterial drugs of class 1.
1, nanofloxacin malate, carrimycin and contezolid
.
In addition, the research and development of the Staphylococcus aureus vaccine has now entered the phase III clinical trial stage
.
1, nanofloxacin malate, carrimycin and contezolid
.
In addition, the research and development of the Staphylococcus aureus vaccine has now entered the phase III clinical trial stage
.
To sum up, since the national "antibacterial restriction order", the sales growth rate of antibacterial drugs in the hospital market has gradually slowed down.
Against the background of the assessment weight of the 2019-09-19, the future antimicrobial drug market will be subject to stricter restrictions, sales will continue to decline, and antimicrobial drug manufacturers will be greatly affected
.
hospital hospital hospital Against the background of the assessment weight of the 2019-09-19, the future antimicrobial drug market will be subject to stricter restrictions, sales will continue to decline, and antimicrobial drug manufacturers will be greatly affected
.
