The U.S.-China research team found a new anti-AIDS protein
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Last Update: 2020-12-16
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Source: Internet
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Author: User
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and U.S. researchers recently found that mice and the human body with anti-AIDS function of the protein, can regulate the immune response to inhibit HIV replication.
Ohio State University, Wuhan University in China and other institutions researchers in the new issue of the United States
reported that past studies have known that mice and the human body a protein called SAMHD1 can degrade dna (deoxybonucleic acid) replication of the substrate, which is HIV, hepatitis B virus and so on in the cell replication necessary. New research has found that this protein can regulate the immune response by binding several key proteins in cells that induce natural immune responses.
the paper's author, Professor Of Ohio State University, explained to Xinhua that pathogenic infections trigger protective immune responses or inflammatory responses, and that immune response activation can be a driving force for virus replication during HIV infection and disease development.
researchers found that after the SAMHD1 protein is modified with phosphorylation, anti-HIV activity is reduced, and some clinically anti-tumor kinase inhibitors can block this modification process, which may enhance the effectiveness of AIDS treatment. (Source: Xinhua News Agency Zhou Zhou)
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