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TERT-BUTYL 3-FORMYLPYRIDIN-4-YLCARBAMATE, also known as 4-Carbamyl-3-butyl-1,2,3,6-tetrahydropyridine (B521), is an organic compound that is widely used in the chemical industry as an intermediate for the production of various chemical products.
In this article, we will explore the upstream and downstream products of B521, and the processes involved in their production.
Upstream Products
The upstream products of B521 are the raw materials required for its production.
The main raw materials used in the production of B521 are 3-butyl-1,2,3,6-tetrahydropyridine (B107), formaldehyde, and hydrogen chloride.
B107 is a colorless liquid with a slightly fruity odor, and it is used as a building block for the synthesis of B521.
Formaldehyde is a colorless gas with a pungent odor, and it is used to form the carbamate group in B521.
Hydrogen chloride is a colorless gas with a strong, unpleasant smell, and it is used to catalyze the reaction between B107 and formaldehyde to form B521.
Downstream Products
The downstream products of B521 are the chemical products that are derived from it.
The main downstream products of B521 are pharmaceuticals, agrochemicals, and other industrial chemicals.
B521 is used as an intermediate in the production of these chemicals, and it is converted into the final products through a series of chemical reactions.
Pharmaceuticals
One of the main downstream products of B521 is pharmaceuticals.
B521 is used in the production of anticancer drugs, anti-inflammatory drugs, and other medicines.
For example, B521 is used in the production of irinotecan, a chemotherapy drug used to treat colorectal cancer.
The production of irinotecan involves a series of chemical reactions, including the conversion of B521 into 9-fluorenone, which is then converted into irinotecan via a series of additional reactions.
Agrochemicals
Another major downstream product of B521 is agrochemicals.
B521 is used in the production of herbicides, pesticides, and other chemicals used in agriculture.
For example, B521 is used in the production of atrazine, a herbicide used to control weeds in crops.
The production of atrazine involves the conversion of B521 into atrazine via a series of chemical reactions.
Industrial Chemicals
B521 is also used in the production of other industrial chemicals, such as solvents, plastics, and dyes.
For example, B521 is used in the production of tetrahydrofuran (THF), a solvent used in the production of resins, coatings, and other industrial products.
The production of THF involves the conversion of B521 into THF via a series of chemical reactions.
Manufacturing Process
The manufacturing process for B521 involves several steps, including synthesis, purification, and bottling.
The synthesis of B521 involves the reaction of B107, formaldehyde, and hydrogen chloride to form the carbamate group in B521.
The purification process involves the removal of impurities and the isolation of pure B521.
Finally, the B521 is bottled and packaged for shipment to its downstream customers.
Conclusion
In summary, TERT-BUTYL 3