The Upstream and Downstream products of DIMETHYL 3,3'-BIPYRIDINE-5,5'-DICARBOXYLATE

Dimethyl 3,3'-bipyridine-5,5'-dicarboxylate (DMBP) is an important intermediate chemical used in the production of several downstream products in the chemical industry.
Upstream products refer to the raw materials required to produce the intermediate chemical, while downstream products refer to the final products that are derived from the intermediate chemical.

One of the upstream products required to produce DMBP is 3,3'-dimethyl-5,5'-dibromo-2,2'-bipyridine, which is derived from the reaction of 2,2'-dibromo-3,3'-dimethyl-5,5'-bipyridin-1-ium iodide with potassium hydroxide.
This bromide is then converted to the corresponding nitrate by treating with nitric acid, and the nitrate is then reduced to the corresponding amine by treatment with lithium aluminum hydride.

Another upstream product required to produce DMBP is 3,3'-dimethyl-5,5'-dicarboxylate dipotassium, which is obtained by treating 3,3'-dimethyl-5,5'-dibromide with potassium hydroxide.
This compound is then reacted with 2,2'-bipyridine to produce DMBP.

Once DMBP is produced, it is used as a starting material to produce a variety of downstream products.
One such downstream product is the antibiotic nifuratel, which is used to treat urinary tract infections.
The synthesis of nifuratel involves several stages, including the conversion of DMBP to 5,5'-diaminomethyl-3,3'-bipyridine, which is then reacted with chloromethylphosphine oxide to form the corresponding intermediate.
This intermediate is then converted to nifuratel through several further stages.

Another downstream product that can be derived from DMBP is the herbicide bentazon.
The synthesis of bentazon involves the reaction of DMBP with 2,4-dichlorophenoxyacetic acid to form the corresponding diacid, which is then condensed with α-hydroxycarboxylic acids to produce the herbicide.

DMBP can also be used as a building block for the synthesis of polymers and other materials.
For example, it can be converted to the corresponding dimethyl ester and then polymerized to produce a polymer with a range of properties.

In conclusion, DMBP is an important intermediate chemical used in the production of several downstream products in the chemical industry, including the antibiotic nifuratel and the herbicide bentazon.
It is produced through several stages from upstream products such as 3,3'-dimethyl-5,5'-dibromo-2,2'-bipyridine and 3,3'-dimethyl-5,5'-dicarboxylate dipotassium.
Once produced, it can be used to synthesize a range of downstream products, including polymers and other materials.