The Upstream and Downstream products of 4-CHLORO-7-HYDROXY-6-METHOXY-QUINOLINE-3-CARBONITRILE

4-Chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile is a compound that is used as an intermediate in the production of various chemicals and pharmaceuticals.
The compound is also known as 4-chloro-7-hydroxymethyl-6-methoxy-1,4-benzoxazepine.

Upstream Products

The production of 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile involves several upstream processes, which include the production of precursor chemicals and raw materials.

One of the key upstream products is paracetamol, which is used to produce the compound.
Paracetamol is a common pain reliever and fever reducer that is used to treat a variety of pain conditions.
The production of paracetamol involves several steps, including the reaction of phenol with acetylene and chlorination with chloroform.

Another key upstream product is aniline, which is used as a precursor in the production of a variety of chemicals, including dyes, drugs, and plastics.
Aniline is produced through the nitration of toluene, which involves the addition of nitric acid to toluene in the presence of a catalyst.

Downstream Products

Once the 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile has been synthesized, it can be used as an intermediate in the production of a variety of downstream products.

One of the key downstream products is the anti-malarial drug, quinine.
Quinine is used to treat malaria and is also used in the production of tonic water.
The production of quinine involves the hydrolysis of 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile with a strong acid such as hydrochloric acid.

Another downstream product is the antibiotic, ciprofloxacin.
Ciprofloxacin is used to treat a variety of bacterial infections and is produced through the synthesis of 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile with a variety of other chemicals.

There are also several other downstream products that can be derived from 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile, including other antibiotics, anti-malarials, and anti-inflammatory drugs.

Manufacturing Process

The production of 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile involves several steps, including the synthesis of precursor chemicals and the reaction of these chemicals to form the final product.

The production process typically begins with the synthesis of aniline, which is then chlorinated with chloroform to produce 4-chloro-7-nitro-6-methoxy-quinoline-3-carbonitrile.
This intermediate is then hydrolyzed with a strong acid, such as hydrochloric acid, to produce 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile.

The final product is then isolated and purified using a variety of techniques, such as chromatography and crystallization.

Market and Industry Trends

The demand for 4-chloro-7-hydroxy-6-methoxy-quinoline-3-carbonitrile and its downstream products is driven by the growing demand for pharmace