The Upstream and Downstream products of 4,5-DICHLORO-6-NITRO-2,3-DIHYDROPYRIDAZIN-3-ONE

The 4,5-dichloro-6-nitro-2,3-dihydropyridazin-3-one, also known as DCDPNO, is an organic compound with a distinctive chemical structure.
This compound has two nitro groups attached to a six-membered aromatic ring, which is further fused to a five-membered pyridazin-3-one ring.
The presence of the nitro and pyridazin-3-one groups makes DCDPNO a versatile building block for the synthesis of various chemicals, drugs, and materials.

Upstream Products of DCDPNO

The upstream products of DCDPNO are the starting materials required for its synthesis.
The initial step in the production of DCDPNO involves the synthesis of 2,3-dihydroxy-6-nitro-4-chloropyridine, which is then converted to DCDPNO through a series of chemical reactions.

One of the key upstream products for the synthesis of DCDPNO is 2,3-dihydroxy-6-nitro-4-chloropyridine, which can be synthesized by treating 2,3-dihydroxy-5-chloropyridine with nitric acid.
This reaction involves the substitution of chlorine atoms for nitric oxide, forming a nitro group.
The resulting intermediate can then be converted to DCDPNO through a series of chemical reactions, including the use of a reductant such as lithium aluminum hydride.

Another upstream product for the synthesis of DCDPNO is 2,3-dihydroxy-6-nitro-4-chloropyridine, which can be synthesized by treating 2,3-dihydroxy-5-chloropyridine with chloroform.
The resulting intermediate can then be converted to DCDPNO through a series of chemical reactions, including the use of a reductant such as lithium aluminum hydride.

Downstream Products of DCDPNO

The downstream products of DCDPNO are the chemicals, drugs, and materials that can be synthesized using DCDPNO as a starting material.
DCDPNO is a versatile building block, making it possible to synthesize a wide range of downstream products.

One of the most important downstream products of DCDPNO is the anti-malarial drug chloroquine.
Chloroquine is a widely used anti-malarial drug that has been used for over 80 years to treat malaria.
It works by disrupting the proliferation of the parasite responsible for malaria in the human body.
The synthesis of chloroquine requires the use of DCDPNO as a starting material, and the final product can be obtained through a series of chemical reactions.

Another downstream product of DCDPNO is the anti-cancer drug primaquine.
Primaquine is used to treat certain types of cancer, including leukemia and lymphoma.
It works by inhibiting the growth and division of cancer cells.
The synthesis of primaquine requires the use of DCDPNO as a starting material, and the final product can be obtained through a series of chemical reactions.

DCDPNO can also be used in the synthesis of agrochemicals and dyes.
For example, it can be used as a building block for the synthesis of herbicides, insecticides, and fungicides.
It can also be used in the synthesis of dyes for textiles, plastics, and inks.

Conclusion

4,5-dichloro-6-nitro-2,3-dihydropyridazin-3-one (DCDPNO) is a versatile building block for the synthesis of various chemicals, drugs, and materials.
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