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3-Chloro-6-(1H-imidazol-1-yl)pyridazine is an important intermediate in the chemical industry, with a wide range of applications in the production of various chemicals and pharmaceuticals.
The upstream and downstream products of this intermediate are closely related to the production and utilization of this compound.
Upstream Products
The upstream products of 3-chloro-6-(1H-imidazol-1-yl)pyridazine are primarily the raw materials required for its synthesis.
These raw materials include chloropyridazine, 1H-imidazole, and pyridazine, which are all chemical precursors that must be obtained from other sources.
The production of these precursors is a complex process that involves several steps, including the purification and isolation of the individual components.
Downstream Products
The downstream products of 3-chloro-6-(1H-imidazol-1-yl)pyridazine are primarily the chemicals and pharmaceuticals that are derived from this intermediate.
Some of the most commonly used downstream products include:
- Pharmaceuticals: 3-chloro-6-(1H-imidazol-1-yl)pyridazine is used in the production of various pharmaceuticals, including drugs for the treatment of bacterial infections, fungal infections, and other medical conditions.
- Agrochemicals: This compound is also used in the production of agrochemicals, such as herbicides and pesticides, which are used to control weeds and pests in crops.
- Catalysts: 3-chloro-6-(1H-imidazol-1-yl)pyridazine is used as a catalyst in various chemical reactions, including the production of plastics and other synthetic materials.
- Photographic chemicals: This compound is used in the production of photographic chemicals, such as developers and fixers, which are used in the photographic industry.
Manufacturing Process
The manufacturing process for 3-chloro-6-(1H-imidazol-1-yl)pyridazine involves several steps, including the synthesis of the raw materials, the purification of the intermediate, and the production of the downstream products.
The synthesis of the raw materials involves the reaction of chloropyridazine and 1H-imidazole, which is then followed by the condensation of the pyridazine ring.
The purification and isolation of the intermediate is carried out using various chromatographic techniques, such as column chromatography and high-performance liquid chromatography (HPLC).
The production of the downstream products involves the reaction of the purified intermediate with other chemicals, such as acetic anhydride and sodium acetate, in the presence of acetic acid.
The reaction produces the desired product, which is then purified and isolated using conventional methods.
Safety and Regulatory Issues
3-chloro-6-(1H-imidazol-1-yl)pyridazine is a hazardous chemical that must be handled with care.
It is classified as a Category 3 carcinogen by the International Agency for Research on Cancer (IARC), which means that it is possibly carcinogenic to humans.
It is also classified as a hazardous substance under various regulations, including the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS) and the European Union's Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation.
Conclusion
3-chloro-6-(1H-imidazol-1-yl)pyridazine is an important intermediate in the chemical industry, with a wide range of applications in the production
