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2-Tert-butylpyrimidin-4-amine is an organic compound that is commonly used as a building block for the synthesis of various chemicals and pharmaceuticals.
In the chemical industry, it is often referred to as a "chemical intermediate," as it is used as a precursor to produce a wide range of downstream products.
In this article, we will explore the upstream and downstream products of 2-Tert-butylpyrimidin-4-amine, and how it is used in the chemical industry.
Upstream Products of 2-Tert-butylpyrimidin-4-amine
The upstream products of 2-Tert-butylpyrimidin-4-amine include the raw materials and intermediates that are used in its synthesis.
One of the most common methods for the synthesis of 2-Tert-butylpyrimidin-4-amine involves the reaction of 2,2'-dithiobis(benzothiazole) with acrylonitrile in the presence of a catalyst, such as ferric chloride.
The starting materials for this reaction are 2,2'-dithiobis(benzothiazole), acrylonitrile, and a solvent, such as toluene.
The intermediates in this process include the dithiobis(benzothiazole) complex, which is formed by the reaction of 2,2'-dithiobis(benzothiazole) with acrylonitrile, and the metal sulfonate complex, which is formed by the addition of ferric chloride.
Downstream Products of 2-Tert-butylpyrimidin-4-amine
The downstream products of 2-Tert-butylpyrimidin-4-amine include the chemicals and pharmaceuticals that are produced using it as a precursor.
One of the most common downstream products of 2-Tert-butylpyrimidin-4-amine is N-[2-[4-[[2-[(2S)-2-tetrahydro-2-oxo-1,3-oxazolidin-3-yl]-6,7-dimethoxyquinazolin-4-yl]amino]-6,7-dimethoxy-5-oxo-3-azabicyclo[3.
1.
0]hex-2-yl]amino]acetamide, also known as LY295654, which is an anti-inflammatory drug that is used to treat autoimmune disorders such as rheumatoid arthritis.
Other downstream products of 2-Tert-butylpyrimidin-4-amine include analgesics, antidepressants, anti-inflammatory agents, and anti-cancer drugs.
Applications of 2-Tert-butylpyrimidin-4-amine
2-Tert-butylpyrimidin-4-amine is a versatile chemical intermediate that is used in a wide range of applications in the chemical industry.
Its ability to act as a precursor to a variety of downstream products makes it a valuable building block in the synthesis of pharmaceuticals and other chemicals.
The high demand for these downstream products has led to a significant increase in the production of 2-Tert-butylpyrimidin-4-amine in recent years, and it is expected to continue to be a vital component in the chemical industry in the coming years.
Challenges in the Production of 2-Tert-butylpyrimidin-4-amine
The production of 2-Tert-butylpyrimidin-4-amine is a complex process that involves several steps, including the reaction of 2,2'-dithiobis(benzoth