-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
2-Piperazinecarboxamide, commonly referred to as PCA, is a chemical compound that is used in a wide range of applications in the chemical industry.
PCA is an organic compound that is synthesized from ammonia and cyclohexanone by a series of chemical reactions.
The reaction scheme for the synthesis of PCA is shown below:
In the first step of the synthesis, cyclohexanone is converted into cyclohexanone oxime by treatment with hydroxylamine.
The oxime is then converted into N-iodoacetamide by treatment with iodine and acetamide.
Finally, the N-iodoacetamide is treated with ammonia to yield PCA.
PCA is an important intermediate in the production of several downstream products, including pharmaceuticals, plastics, and dyes.
One of the main downstream products of PCA is hydroxypropyl cellulose, which is a thickening agent used in a wide range of products, including food, cosmetics, and pharmaceuticals.
PCA is also used in the production of the antibiotic vancomycin and the anti-inflammatory drug celecoxib.
In addition to its use as an intermediate in the production of downstream products, PCA is also used as a catalyst in chemical reactions.
It is commonly used as a catalyst in the production of polyethylene terephthalate (PET), a plastic used in bottles and other packaging materials.
PCA is also used as a catalyst in the production of polyurethanes, a type of plastic used in a wide range of applications, including in the manufacture of foam insulation and coatings.
The upstream products of PCA are the raw materials that are used in the synthesis of PCA.
These raw materials include cyclohexanone, hydroxylamine, iodine, and ammonia.
Cyclohexanone is a type of alkene that is commonly used as a solvent and in the production of plastics.
Hydroxylamine is an ammine that is used in the production of fertilizers and other chemical products.
Iodine is a halogen that is used in the production of iodide salts and other chemical products.
Ammonia is a type of gas that is used in the production of fertilizers and other chemical products.
The production of PCA involves several steps, including the synthesis of the raw materials, the conversion of the raw materials into PCA, and the purification of PCA to remove any impurities.
The synthesis of PCA involves the conversion of cyclohexanone oxime into N-iodoacetamide by treatment with iodine and acetamide.
The N-iodoacetamide is then treated with ammonia to yield PCA.
The purification of PCA is an important step in the production process, as it ensures that the final product is of the desired quality and is free from impurities.
The purification process typically involves the use of chromatography, which separates the PCA from other impurities based on their chemical properties.
In conclusion, 2-Piperazinecarboxamide is an important intermediate in the production of several downstream products, including hydroxypropyl cellulose, vancomycin, and celecoxib.
It is also used as a catalyst in the production of polyethylene terephthalate and polyurethanes.
The upstream products of PCA include cyclohexanone, hydroxylamine, iodine, and ammonia, which are synthesized through a series of chemical reactions and then purified to yield PCA.
The production of PCA is an important process in the chemical industry, as it is used as an intermediate in the production of several important chemical products.