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1-(6-Pyridazinyl)piperazine, commonly abbreviated as PZP, is a heterocyclic compound with a structure consisting of a six-membered aromatic ring containing a nitrogen atom and a five-membered ring with a piperazine functional group attached to it.
This organic compound has a wide range of applications in various industries, including the chemical industry.
In the chemical industry, PZP is used as an intermediate chemical in the production of various downstream products.
Downstream products are the end products that are derived from the reaction of PZP with other chemicals.
One of the most common downstream products of PZP is the pharmaceutical drug fexofenadine, which is used to treat allergy symptoms.
PZP is converted into fexofenadine through a series of chemical reactions that involve the substitution of different functional groups on the PZP molecule.
This process requires the use of various chemical reagents and solvents and can be carried out using a variety of synthetic methods.
Another downstream product of PZP is the antimalarial drug artesunate.
Artesunate is derived from PZP through a series of chemical reactions that involve the introduction of a methyl group and the substitution of the piperazine group with a sulfonamide group.
This process requires the use of reagents such as methyl iodide and sulfuric acid and can be carried out using various synthetic methods.
PZP is also used as an intermediate in the production of other pharmaceutical drugs, such as the HIV protease inhibitor ritonavir and the antiepileptic drug levetiracetam.
In addition to its use in pharmaceuticals, PZP is also used in the production of other chemical products, such as dyes, fragrances, and plastics.
Upstream products are the raw materials or intermediates that are used to produce PZP and other downstream products.
One of the most common upstream products of PZP is pipiridine, which is a precursor to PZP.
Pipiridine is synthesized through a series of chemical reactions that involve the oxidation of aniline, a compound consisting of a six-membered aromatic ring with a nitrogen atom attached to it.
This process requires the use of various reagents and solvents and can be carried out using various synthetic methods.
Another upstream product of PZP is 2-phenyl-1,3-oxazepine, which is used as a precursor to PZP.
2-phenyl-1,3-oxazepine is synthesized through a series of chemical reactions that involve the condensation of aniline with another compound called benzaldehyde.
This process requires the use of various reagents and solvents and can be carried out using various synthetic methods.
In addition to these upstream products, PZP can also be synthesized from other compounds such as pyridine, piperidine, and N-methyl Piperazine.
These compounds can serve as precursors to PZP through a series of chemical reactions that involve the substitution of functional groups on the molecule.
Overall, 1-(6-Pyridazinyl)piperazine is an important intermediate chemical in the production of various downstream products in the chemical industry.
The upsstream chemicals such as pipiridine and 2-phenyl-1,3-oxazepine are also important in the production of PZP.
PZP is used in the production of various pharmaceutical drugs, such as fexofenadine, artesunate, ritonavir and levetiracetam.
Its application in pharmaceuticals and other chemical products, such as dyes, fragrances, and plastics