The teams of Zou Zhiyong and Huang Yangmu revealed the trend of tuberculosis burden among HIV-negative and HIV-positive populations in BRICS countries

Recently, The Lancet - Part of the LANCET Discovery Science The journal published a study by the Peking University School of Public Health on H IV negative and HIV positive people in the BRICS countries Time trends in tuberculosis mortality across the BRICS: an age-period-cohort analysis for the GBD 2019.
EClinicalMedicine.
2022 Sep 17; 53:101646.
doi: 10.
1016/j.
eclinm.
2022.
101646）
。 This study suggests the weak links in tuberculosis prevention and control in BRICS countries, provides information for the adjustment of tuberculosis prevention and control strategies and resource allocation, and provides reference for other countries with high tuberculosis burden and even the world to formulate tuberculosis prevention and control strategies.

Figure 1 Screenshot of the official research paper

TB leads the list of deaths from a single infectious agent and is a major global health challenge
.
A series of global actions have been launched to end the TB epidemic, but in the past decade many countries have newly diagnosed TB patients The number of people continues to grow
.
Globally, there were an estimated 9.
65 million new TB cases and 1.
4 million deaths in 2019.

The BRICS countries (Brazil, Russian Federation, India, China and South Africa) are all countries with a high burden of TB, 2019 A total of 549 522 people died of tuberculosis in BRICS countries, accounting for 39.
3%
of global tuberculosis deaths.

BRICS countries have a high burden of AID/TB CO-INFECTION (HIV-TB), but there are currently no studies to analyse TB trends by HIV prevalence classification , nor can it be distinguished between cohort effects and period effects
.
The results of this study show that among the BRICS countries, Brazil is the first to effectively control the rising trend
of HIV-TB mortality.
HIV-negative middle-aged adults (35-55 years old) in India, HIV-negative men over 50 years of age in South Africa There is a trend
towards increased burden among HIV-positive people, as well as among women aged 45-55 in Russia.
The increased risk of TB death among HIV-positive people in China in the period 2010-2019 and in the post-1980 cohort of young births requires special attention
。 Brazil and China achieved better TB control outcomes
in H IV-positive and H IV-negative populations, respectively.
Its successful prevention and control experience suggests that India and South Africa should pay more attention to primary health care, pay attention to HIV-TB groups and strengthen social protection measures
.
BRICS and other countries with a high burden of TB should pay attention to vulnerable groups, pay attention to differences in national circumstances and the challenges posed by HIV/AIDS, and develop stronger and more targeted public health strategies for different priority groups to achieve the strategic goals of
stopping TB.

Fig.
2 Trends in tuberculosis burden among H IV-negative and HIV-positive populations in BRICS countries from 1990 to 2019

Fig.
3 Analysis results of the age-period-cohort model of the H IV-positive population in BRICS countries from 1990 to 2019

As an official research paper led by collaborators on the global burden of disease, Zhiyong Zou and Guangqi Liu from the School of Public Health of Peking University are co-first authors and Yangmu Huang is the corresponding author
.

(School of Public Health, Peking University)