The Synthetic Routes of (E)-2-chloro-3-iMino-N,N-diMethylprop-1-en-1-aMine hydrochloride

(E)-2-chloro-3-iminodimethylprop-1-en-1-amine hydrochloride, also known as ECI-120, is an important raw material in the chemical industry.
It is used as a building block for the synthesis of various chemicals and pharmaceuticals.
There are several synthetic routes available for the synthesis of ECI-120, some of which are more commonly used than others.

One of the most popular synthetic routes for the synthesis of ECI-120 is the Amadori-Chichibabin-Deuparquet reaction.
This reaction involves the use of a primary amine and a carbonyl compound in the presence of sodium hydroxide and dimethylformamide (DMF) as solvents.
The Amadori-Chichibabin-Deuparquet reaction results in the formation of a secondary amine, which is then reduced using hydrogen gas in the presence of a reducing agent such as lithium aluminum hydride (LiAlH4) to yield ECI-120.

Another synthetic route for the synthesis of ECI-120 involves the use of the hydrochloride salt of N,N-dimethylamino-2-chloro-1-propanamine.
This synthetic route involves the reaction of N,N-dimethylformamide with N-chlorosuccinimide in the presence of a catalyst such as hydrochloric acid.
The resulting product is then hydrolyzed using a strong acid such as sulfuric acid to yield ECI-120.

Yet another synthetic route for the synthesis of ECI-120 involves the use of the phosphoramidite method.
This method involves the use of a primary amine and a halogenated compound in the presence of a phosphoramidite catalyst.
The resulting product is then deprotected using a strong acid such as hydrochloric acid to yield ECI-120.

The synthetic routes outlined above are some of the most commonly used methods for the synthesis of ECI-120.
However, other synthetic routes may also be used, depending on the specific requirements of the synthesis process.
For example, some synthetic routes involve the use of reagents such as olefins, diazo compounds, and other halogenated compounds.

Overall, the synthetic routes for the synthesis of ECI-120 are diverse and can involve a variety of different reagents and catalysts.
However, the Amadori-Chichibabin-Deuparquet reaction and the hydrochloride salt of N,N-dimethylamino-2-chloro-1-propanamine are two of the most commonly used synthetic routes.
These routes are relatively straightforward and can yield high yields of ECI-120 with good purity.