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    Home > Active Ingredient News > Antitumor Therapy > The Synthetic Routes of 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL

    The Synthetic Routes of 4-AMINO-6-METHYL-1,3,5-TRIAZIN-2-OL

    • Last Update: 2023-04-25
    • Source: Internet
    • Author: User
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    4-Amino-6-methyl-1,3,5-triazine-2-ol is a versatile chemical compound that has various applications in the chemical industry.
    It is commonly used as a building block for the synthesis of other chemicals and can be derived from several synthetic routes.
    In this article, we will discuss the different synthetic routes for the preparation of 4-amino-6-methyl-1,3,5-triazine-2-ol.


    One of the most common methods for the synthesis of 4-amino-6-methyl-1,3,5-triazine-2-ol is the treatment of aniline with a mixture of hydrochloric acid and sodium nitrite in the presence of a solvent such as acetic acid or sulfuric acid.
    The reaction produces the desired compound along with the formation of nitrosobenzene as a byproduct.


    Another synthetic route for 4-amino-6-methyl-1,3,5-triazine-2-ol involves the reaction of melamine with formaldehyde in the presence of a solvent such as water or methanol.
    The reaction produces the desired compound along with the formation of cyanamide as a byproduct.


    Yet another method for the synthesis of 4-amino-6-methyl-1,3,5-triazine-2-ol involves the reaction of methyl-trioxane-2-amine with chloroacetic acid in the presence of a solvent such as dichloromethane or benzene.
    The reaction produces the desired compound along with the formation of carbon dioxide and methanol as byproducts.


    4-Amino-6-methyl-1,3,5-triazine-2-ol can also be synthesized by the reaction of 4-aminobenzamide with 2,4-dinitrophenylhydrazine in the presence of a solvent such as pyridine or acetic acid.
    The reaction produces the desired compound along with the formation of nitrochlorobenzene as a byproduct.


    Another synthetic route for the preparation of 4-amino-6-methyl-1,3,5-triazine-2-ol involves the reaction of 4-methoxypyrrole with dimethyl sulfate in the presence of a solvent such as acetonitrile or dichloromethane.
    The reaction produces the desired compound along with the formation of dimethyl sulfoxide as a byproduct.


    In conclusion, there are several synthetic routes available for the preparation of 4-amino-6-methyl-1,3,5-triazine-2-ol.
    These routes involve the reaction of various reactants, including aniline, melamine, methyl-trioxane-2-amine, 4-aminobenzamide, and 4-methoxypyrrole.
    The choice of synthetic route depends on the availability of the reactants and the desired yield of the product.
    The synthetic routes discussed in this article are commonly used in the chemical industry for the production of 4-amino-6-methyl-1,3,5-triazine-2-ol, which is widely used as a building block for the synthesis of other chemicals.


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