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The Synthesis of 4,4',4''-TRI-TERT-BUTYL-2,2':6',2''-TERPYRIDINE: An Overview of Current Methods and Future Directions in the Chemical Industry
4,4',4''-TRI-TERT-BUTYL-2,2':6',2''-TERPYRIDINE, also known as THT, is a synthetic molecule with a unique structural formula and a wide range of potential applications in the chemical industry.
This molecule has been studied extensively in recent years, and several synthetic routes have been developed to produce it in high yield and purity.
In this article, we will review the current synthetic methods for THT and discuss the potential applications and future directions for this molecule in the chemical industry.
- Hydrogenation of N-(2,2-dimethyl-4,4,5,5-tetramethyl-1,3-oxazolidin-3-yl)-2-(tert-butyl)-4,4',4''-triamino-1,3,2-dioxaborole-
This method involves the hydrogenation of N-(2,2-dimethyl-4,4,5,5-tetramethyl-1,3-oxazolidin-3-yl)-2-(tert-butyl)-4,4',4''-triamino-1,3,2-dioxaborole- to produce THT.
This method involves the reduction of the nitrogen atom in the precursor molecule to form the THT molecule.
This method is relatively simple and has been used to produce THT in high yield.
- Palladium-Catalyzed Stille Cross-Coupling
This method involves the use of palladium-based catalysts to perform a Stille cross-coupling reaction between the precursor molecule and a halogenated palladium complex.
This method allows for the formation of the C-C bond between the precursor molecule and the THT molecule, producing the final product.
This method is highly efficient and has been used to produce THT in high yield.
- Suzuki-Miyaura Cross-Coupling
This method involves the use of a Suzuki-Miyaura cross-coupling reaction to form the C-C bond between the precursor molecule and the THT molecule.
This method uses a boron-based catalyst to facilitate the reaction, which results in the formation of the final product.
This method is highly efficient and has been used to produce THT in high yield.
- Sonogashira Coupling Reaction
This method involves the use of a Sonogashira coupling reaction to form the C-C bond between the precursor molecule and the THT molecule.
This method uses a palladium-based catalyst to facilitate the reaction, which results in the formation of the final product.
This method is highly efficient and has been used to produce THT in high yield.
- Hydrogenation of 4,4',4''-TRI-TERT-BUTYL-2,2':6',2''-TERPYRIDINE Dichloride
This method involves the hydrogenation of 4,4',4''-TRI-TERT-BUTYL-2,2':6',2''-TERPYRIDINE dichloride to produce THT.
This method involves the reduction of the nitrogen atom in the precursor molecule to form the THT molecule.
This method is relatively simple and has been used to produce THT in high yield.
- Electrophilic Substitution Reaction
This method involves the use of an electrophilic substitution reaction to form the C-C bond between the precursor molecule and the THT molecule.
This method uses a