The Synthetic Routes of 3-Pyridazinecarboxylicacid,6-methyl-,ethylester(9CI)

3-Pyridazinecarboxylicacid,6-methyl-,ethylester, commonly referred to as 9CI, is a chemical compound that finds extensive use in various industries, including the chemical industry.
This compound can be synthesized through several synthetic routes, each with its unique set of advantages and disadvantages.
In this article, we will discuss three common synthetic routes for the synthesis of 9CI and their applications in the chemical industry.

Route 1: via Pyridine-2,6-dicarboxylic acid

One of the most common synthetic routes for the synthesis of 9CI involves the reaction of pyridine-2,6-dicarboxylic acid with ethyl acetate in the presence of a strong acid catalyst such as hydrochloric acid.
The reaction results in the formation of 3-pyridazinecarboxylicacid,6-methyl-,ethylester, which can be further purified and used as required.

This route is commonly used in the chemical industry as it is a relatively simple and inexpensive process.
The reaction can be carried out at room temperature, and the resulting product can be easily purified using standard chromatography techniques.
Additionally, the starting material, pyridine-2,6-dicarboxylic acid, is readily available and inexpensive, making the overall process cost-effective.

Route 2: via Pyridine-3,5-dicarboxylic acid

Another commonly used synthetic route for the synthesis of 9CI involves the reaction of pyridine-3,5-dicarboxylic acid with ethyl bromide in the presence of a Lewis acid catalyst such as aluminum chloride.
The reaction results in the formation of the desired product, which can be further purified and used as required.

This route is also commonly used in the chemical industry due to its simplicity and cost-effectiveness.
The reaction can be carried out at room temperature, and the resulting product can be easily purified using standard chromatography techniques.
Additionally, the starting material, pyridine-3,5-dicarboxylic acid, is also readily available and inexpensive, making the overall process cost-effective.

Route 3: via Pyridine-3,6-dicarboxylic acid

A third synthetic route for the synthesis of 9CI involves the reaction of pyridine-3,6-dicarboxylic acid with methyl acetate in the presence of a strong acid catalyst such as hydrochloric acid.
The reaction results in the formation of the desired product, which can be further purified and used as required.

This route is also commonly used in the chemical industry due to its simplicity and cost-effectiveness.
The reaction can be carried out at room temperature, and the resulting product can be easily purified using standard chromatography techniques.
Additionally, the starting material, pyridine-3,6-dicarboxylic acid, is also readily available and inexpensive, making the overall process cost-effective.

Advantages of Synthetic Routes

The synthetic routes described above offer several advantages in the chemical industry.
Firstly, they are relatively simple and inexpensive, which makes them ideal for large-scale production.
Additionally, the reactions can be carried out at room temperature, which reduces the energy requirements and costs of the process.

Furthermore, the resulting product can be easily purified using standard chromatography techniques, which ensures high purity and quality of the final product.
This is particularly important in the chemical industry, where the quality of the product is critical for various applications.

Applications of 9CI

9CI finds extensive use in various applications in the chemical industry.
One of the most common applications is as an intermediate for the synthesis of various pharmaceuticals, agrochemicals, and other chemical products.

Additionally, 9CI is used as a building block for the synthesis of polymers,