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2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) is a synthetic compound that is commonly used in various applications in the chemical industry.
This compound is synthesized through several steps, which are collectively known as the synthetic routes.
The synthetic routes of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) involve several steps, including the synthesis of the individual components and their subsequent combination to form the final compound.
The synthetic routes of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) can vary depending on the method and the starting materials used.
Some of the common methods used in the synthesis of this compound include chemical reactions, such as condensation reactions and substitution reactions, as well as precipitation reactions.
One of the common synthetic routes of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) involves the following steps:
- Synthesis of 2H-Indol-2-one: This compound is synthesized by heating indole with hydrochloric acid.
- Synthesis of 4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)amine: This compound is synthesized by reacting 1-piperazinyl)ethyl)amine with 1,2-benzisothiazol-3-one in the presence of a base.
- Synthesis of 6-chloro-1,3-dihydro-2H-indol-2-one: This compound is synthesized by treating 2H-Indol-2-one with chloroform and a base.
- Synthesis of the final compound: The final compound is synthesized by combining the three compounds obtained in the previous steps using a suitable reaction conditions.
Another common synthetic route of 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) involves the following steps:
- Synthesis of 2H-Indol-2-one: This compound is synthesized by heating indole with hydrochloric acid.
- Synthesis of 4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)amine: This compound is synthesized by reacting 1-piperazinyl)ethyl)amine with 3-chloromethyl-1,2-benzisothiazolone in the presence of a base.
- Synthesis of 6-chloro-1,3-dihydro-2H-indol-2-one: This compound is synthesized by treating 2H-Indol-2-one with chloroform and a base.
- Synthesis of the final compound: The final compound is synthesized by combining the three compounds obtained in the previous steps using a suitable reaction conditions.