The Synthetic Routes of 2-pyrimidinemethanol,4,6-dimethoxy-

2-Pyrimidinemethanol, 4,6-dimethoxy is a versatile organic compound that finds various applications in the chemical industry.
The compound can be synthesized through several routes, and the choice of route depends on various factors such as cost, availability of reagents, and desired yield.
In this article, we will discuss some of the synthetic routes for 2-pyrimidinemethanol, 4,6-dimethoxy.

Route 1:via 2-pyrimidone-4,6-diamine

This route involves the synthesis of 2-pyrimidone-4,6-diamine, which is then reduced to 2-pyrimidinemethanol, 4,6-dimethoxy.
The reaction can be carried out by using various reducing agents such as lithium aluminum hydride (LiAlH4) or hydrogen in the presence of a catalyst such as palladium on barium sulfate.
The reaction conditions are as follows:

• 2-Pyrimidone-4,6-diamine is dissolved in a solvent such as acetonitrile or ethanol.
  
• A solution of LiAlH4 is added gradually to the solution while stirring.
  
• The reaction is then quenched with water or an aqueous solution of sodium bicarbonate.
  
• The product is then filtered, and the solvent is removed under reduced pressure.
  
• The resulting residue is then treated with a reducing agent such as hydrogen in the presence of a catalyst such as palladium on barium sulfate.
  

Route 2:via 2-pyrimidin-4-ol

This route involves the synthesis of 2-pyrimidin-4-ol, which is then converted to 2-pyrimidinemethanol, 4,6-dimethoxy.
The reaction can be carried out by using various reagents such as dimethoxy sulfide or chloride.
The reaction conditions are as follows:

• 2-Pyrimidin-4-ol is dissolved in a solvent such as methanol or ethanol.
  
• A solution of dimethoxy sulfide or chloride is added gradually to the solution while stirring.
  
• The reaction is then allowed to proceed at room temperature for a certain period.
  
• The product is then filtered, and the solvent is removed under reduced pressure.
  
• The resulting residue is then treated with a reducing agent such as lithium aluminum hydride or hydrogen in the presence of a catalyst such as palladium on barium sulfate.
  

Route 3:via 2-pyrimidin-2-ol

This route involves the synthesis of 2-pyrimidin-2-ol, which is then converted to 2-pyrimidinemethanol, 4,6-dimethoxy.
The reaction can be carried out by using various reagents such as hydroxylamine or hydrazine.
The reaction conditions are as follows:

• 2-Pyrimidin-2-ol is dissolved in a solvent such as methanol or ethanol.
  
• A solution of hydroxylamine or hydrazine is added gradually to the solution while stirring.
  
• The reaction is then allowed to proceed at room temperature for a certain period.
  
• The product is then filtered, and the solvent is removed under reduced pressure.
  
• The resulting residue is then treated with a reducing agent such as lithium aluminum hydride or hydrogen in the presence of a catalyst such as palladium on barium sulfate.
  

In conclusion, 2-pyrimidinemethanol, 4,6-dimethoxy can be synthesized via several routes, and the choice of route depends on various