The Synthetic Routes of 2-Pyrimidinamine, 5-ethenyl- (9CI)

2-Pyrimidinamine, 5-ethenyl- (9CI) is a synthetic compound that is commonly used in the chemical industry.
It is a versatile molecule that has a wide range of applications in various fields, including pharmaceuticals, agriculture, and materials science.
The synthetic routes of 2-pyrimidinamine, 5-ethenyl- (9CI) can be broadly classified into two categories: chemical synthesis and biotechnological synthesis.

Chemical Synthesis:
The chemical synthesis of 2-pyrimidinamine, 5-ethenyl- (9CI) involves the use of various chemical reactions such as alkylation, halogenation, and condensation reactions.
The following steps outline one possible synthesis route for this compound:

Step 1: Production of Nitroethane
The first step in the chemical synthesis of 2-pyrimidinamine, 5-ethenyl- (9CI) involves the production of nitroethane.
This can be achieved by the nitration of ethylene with nitric acid.

Step 2: Production of 2-PyrimidineCarbaldehyde
The next step in the synthesis involves the production of 2-pyrimidinecarbaldehyde.
This can be achieved by the dehydrogenation of 2-pyrimidineamine using heat or a chemical reducing agent such as lithium aluminum hydride (LiAlH4).

Step 3: Production of N-Ethyl-2-PyrimidineCarbaldehyde
The next step involves the production of N-ethyl-2-pyrimidinecarbaldehyde.
This can be achieved by the reaction of 2-pyrimidinecarbaldehyde with ethyl iodide in the presence of a solvent such as acetonitrile.

Step 4: Production of N-(2-Ethenyl-6- nitro-4-pyrimidinyl)acetamide
The final step involves the production of N-(2-ethenyl-6-nitro-4-pyrimidinyl)acetamide.
This can be achieved by the reaction of N-ethyl-2-pyrimidinecarbaldehyde with 2-chloro-6-nitropyrimidine in the presence of a solvent such as acetonitrile and quinoline.

Biotechnological Synthesis:
The biotechnological synthesis of 2-pyrimidinamine, 5-ethenyl- (9CI) involves the use of microorganisms such as bacteria or yeast.
These microorganisms are genetically modified to produce the desired compound.
The following steps outline one possible synthesis route for this compound:

Step 1: Production of Nitroethane
The first step in the biotechnological synthesis of 2-pyrimidinamine, 5-ethenyl- (9CI) involves the production of nitroethane.
This can be achieved by the expression of a nitroreductase enzyme in the microorganism.

Step 2: Production of 2-PyrimidineCarbaldehyde
The next step involves the production of 2-pyrimidinecarbaldehyde.
This can be achieved by the expression of a pyrimidine carbaldehyde synthase enzyme in the microorganism.

Step 3: Production of N-Ethyl-2-PyrimidineCarbaldehyde
The next step involves the production of N-ethyl-2-pyrimidinecarbaldehyde.
This can be achieved by the expression of an ethyltransferase enzyme in the microorganism.

Step 4: Production of N-(2-Ethenyl-6-