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    Home > Medical News > Medical World News > The Synthetic Routes of 2-Amino-3,5-dibromopyrazine

    The Synthetic Routes of 2-Amino-3,5-dibromopyrazine

    • Last Update: 2023-05-07
    • Source: Internet
    • Author: User
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    2-Amino-3,5-dibromopyrazine is a synthetic chemical compound that has a wide range of applications in the chemical industry.
    It is commonly used as a building block for the synthesis of pharmaceuticals, agrochemicals, and other industrial chemicals.
    The synthetic routes of 2-amino-3,5-dibromopyrazine can be classified into several categories, including chemical, biochemical, and synthetic.


    The chemical route involves the use of chemical reactions to synthesize 2-amino-3,5-dibromopyrazine.
    This route typically involves the use of hazardous reagents and requires strict safety measures to prevent accidents.
    One of the most common chemical routes is the reaction of 3,5-dibromo salicylaldehyde with ammonia, which yields 2-amino-3,5-dibromopyrazine.
    This reaction requires the use of caustic soda and results in the production of hazardous byproducts, including sodium bromide and hydrogen bromide gas.


    The biochemical route involves the use of microorganisms to synthesize 2-amino-3,5-dibromopyrazine.
    This route is less hazardous than the chemical route and has lower production costs.
    One of the most common biochemical routes is the reaction of 3,5-dibromo salicylaldehyde with microorganisms such as Escherichia coli or Bacillus subtilis, which contain the enzyme 3,5-dibromo salicylaldehyde dehydrogenase.
    This enzyme converts 3,5-dibromo salicylaldehyde into 2-amino-3,5-dibromopyrazine, which is then isolated from the microorganisms.


    The synthetic route involves the use of synthetic methodologies to synthesize 2-amino-3,5-dibromopyrazine.
    This route typically involves the use of modern organic synthesis techniques, such as asymmetric synthesis, lactamization, and E-Alkylation.
    One of the most common synthetic routes involves the reaction of 3,5-dibromo salicylaldehyde with a chiral amine catalyst, such as chiral amine-2, followed by hydrolysis to yield 2-amino-3,5-dibromopyrazine.


    In conclusion, 2-amino-3,5-dibromopyrazine is a versatile synthetic chemical compound that has a wide range of applications in the chemical industry.
    The synthetic routes of 2-amino-3,5-dibromopyrazine can be classified into several categories, including chemical, biochemical, and synthetic.
    The chemical route involves the use of hazardous reagents and requires strict safety measures, while the biochemical route involves the use of microorganisms and has lower production costs.
    The synthetic route involves the use of modern organic synthesis techniques and yields the highest purity of 2-amino-3,5-dibromopyrazine.


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