The Synthetic Routes of 2,7-DibroMo-9,9-difluoro-9H-fluorene

2,7-DibroMo-9,9-difluoro-9H-fluorene is an important synthetic intermediate in the chemical industry, with a wide range of applications in the production of materials, pharmaceuticals, and agricultural products.
The synthesis of this compound has been the subject of extensive research in recent years, and several synthetic routes have been developed to produce it in high yield and purity.

One of the most common synthetic routes for 2,7-dibromo-9,9-difluoro-9H-fluorene involves the reaction of 2,7-dibromo-9H-fluorene with a mixture of sulfuric acid and fluorosulfuric acid.
This reaction results in the formation of a mixture of sulfonated and fluorinated derivatives of 2,7-dibromo-9H-fluorene, which can be separated and purified by various methods, such as crystallization, chromatography, and precipitation.

Another synthetic route involves the reaction of 2,7-dichloro-9,9-difluoro-9H-fluorene with a Lewis acid catalyst, such as aluminum chloride or boron trifluoride, in the presence of a solvent, such as toluene or xylene.
This reaction results in the formation of the desired product, which can be purified by filtration and washing with a solvent, such as ether or hexane.

A third synthetic route involves the reaction of 2,7-dibromo-9,9-difluoro-9H-fluorene with a peroxy acid, such as peroxyacetic acid or peroxypropionic acid, in the presence of a solvent, such as acetonitrile or dimethylformamide.
This reaction results in the formation of the desired product, which can be purified by filtration and washing with a solvent, such as ether or hexane.

The synthetic routes described above have several advantages and disadvantages, and the choice of route depends on factors such as the desired yield, purity, cost, and availability of reagents.
The synthetic routes can also be modified and optimized by changing the reaction conditions, such as the temperature, pressure, and concentration of the reagents, to improve the efficiency and selectivity of the reactions.

In conclusion, the synthetic routes of 2,7-dibroMo-9,9-difluoro-9H-fluorene are complex and multistep processes that involve the use of various reagents, solvents, and catalysts.
The choice of route depends on factors such as the desired yield, purity, cost, and availability of reagents, and the reaction conditions can be modified and optimized to improve the efficiency and selectivity of the reactions.
The synthetic routes described above are important in the production of a wide range of materials, pharmaceuticals, and agricultural products, and further research is necessary to improve their efficiency and reduce their environmental impact.