The study found that many young stomach cancer patients suffer from obvious diseases

new study from the Mayo Clinic found that many people under the age of 60 with stomach cancer suffer from diseases that are genetically and clinically different. The study found that this new, early-onset form usually grows and spreads faster, has a worse prognostic period, and is more resistant to traditional chemotherapy than stomach cancer in older adults. The study was recently published in the journal Surgery.
Although the incidence of stomach cancer in older patients has declined for decades, this early onset of cancer is on the rise and now accounts for more than 30 per cent of gastric cancer diagnosed.
“ I think it's a shocking trend because stomach cancer is a devastating disease," said Travis Grotz, M.D., a surgical oncologist at the Mayo Clinic. The
studied 75,225 cases using multiple cancer databases to assess stomach cancer statistics from 1973 to 2015. Today, the average age of people diagnosed with stomach cancer is 68, but people in their 30s, 40s and 50s are at greater risk than before.
Although there is no clear definition of cut-off age for early and late-on-death stomach cancer, the researchers found that they were correct regardless of whether they used the cut-off age distinction of 60, 50 or 40. The researchers found that the incidence of advanced stomach cancer decreased by 1.8% per year during the study period, while the incidence of early gastric cancer decreased by 1.9% per year from 1973 to 1995 and then by 1.5% by 2013. The proportion of early-oncular stomach cancer has doubled from 18 per cent in 1995 to more than 30 per cent today.
"Usually, we find patients in their 70s diagnosed with stomach cancer, but more and more are diagnosed in their 30s and 50s," Dr. Groz said. Dr
, added that the increase in early morbidity did not come from early detection or screening. "There is no universal screening method for stomach cancer, and in fact younger patients show advanced stomach cancer than older patients, " he said. In
, the researchers found that, in addition to being more deadly, early onset of stomach cancer was also genetically and molecularly significant. In addition, traditional older Americans, such as smokers, do not appear to have any risk factors for stomach cancer associated with their early onset.
"Especially among young patients, it is hoped that such research will raise awareness and increase physicians' suspicion of stomach cancer," Dr. Groz said. He added that young people should see a doctor if they feel full after meals, or have reflow, abdominal pain, unexpected weight loss and difficulty eating.
Stomach cancer is the 16th most common cancer in the United States, according to the American Cancer Society. Its five-year survival rate is 31.5 percent, according to the U.S. National Cancer Institute, and an estimated 27,510 new cases will occur by 2019. The World Health Organization reports that cancer is the second most common cause of death in the world in 2018, while stomach cancer is the third most common cause of death in the year.Next, the team hopes to better identify risk factors for early-stage stomach cancer through the Rochester Epidemiology Program and other potentially large databases. （cyy123.com）