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XINHUA News Agency, Beijing, September 7 (Xinhua) -- "Reference News" published on the U.S. Daily Science Website on the 7th" related to the increased risk of Alzheimer's disease commonly used drugs.
The treatment of diseases such as allergies, colds, high blood pressure and urinary incontinence may increase the risk of cognitive decline, especially in older people, according to a team of scientists led by researchers at the University of California, San Diego School of Medicine.
the results of the study were published On September 2, 2020 on the website of the Journal of Neurology of the American Academy of Neurology.
, anticholinel energy drugs are widely used to treat dozens of diseases, large and small.
some of these anticholinel drugs require a doctor's prescription to buy, while others can be purchased directly over the counter at the pharmacy.
they work by preventing acetylcholine, a neurotransmitter or chemical messenger vital to memory function, from binding to a subject on a particular nerve cell.
effect is the suppression of side-sensing nerve impulses, which are associated with a variety of unconscious muscle activities, such as muscle activity in the gastrointestinal tract and lungs, as well as human physiological functions such as salivation, digestion and urination.
researchers said that subjects who took at least one anticholinear energy drug when their metrics were at the baseline and were followed for 10 years were 47 percent more likely to develop mild cognitive impairment than 20 percent who did not.
cognitive impairment is often a precursor to dementia such as Alzheimer's disease.
Dr Lisa Delano-Wood, an associate professor in the Department of Psychiatry at the University of California, San Diego School of Medicine and one of the study's authors, said: "This study suggests that reducing the use of anticholinear drugs before cognitive problems occur may be important in preventing negative effects on memory and thinking skills in the future, especially in people at greater risk of Alzheimer's disease."
" 688 adults with an average age of 74 participated in the study and were grouped by sex.
the study, none of the subjects had cognitive or memory problems and reported whether they were taking anticholinear drugs.
accounted for one-third of them, with an average of 4.7 anticholinel drugs per person.
subjects underwent an annual comprehensive cognitive test for up to 10 years.
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