The study found a new disease-caused gene for allergic rhinitis

international research team says they have identified 20 new risk genes linked to allergic rhinitis, which could find new targets for the prevention and treatment of allergic rhinitis.
Allergic rhinitis, also known as hay fever, patients are mainly allergic to pollen, dust mites, animal hair, manifested as bursts of sneezing, nose a large number of watery snot, itchy nose, serious cases will appear itchy eyes, nasal congestion, loss of sense of smell and other symptoms.
The international team, led by the Munich Research Centre in Helmholtz, Germany, reported in the new issue of the British journal
that they collected data on nearly 900,000 people and conducted a net-pulling search of risk genes associated with allergic rhinitis to find genetic differences between allergic rhinitis patients and healthy people.
researchers first compared the genomes of 60,000 patients and 150,000 healthy people in the control group and identified 42 risk genes associated with allergic rhinitis, some of which have been documented in the study literature.
, the researchers compared the genomes of another 60,000 patients with 620,000 healthy people, confirming that 20 previously unrealed risk genes were associated with allergic rhinitis. The researchers say the genes identified could explain about 8 percent of allergic rhinitis cases.
researchers used the database to further confirm the function of these genes, finding that most of them were related to the immune system, and that the risk genes for allergic rhinitis were highly complex with those for autoimmune diseases.
researchers say the discovery of allergic rhinitis risk genes could help to understand the causes of the disease, but the genes found so far have limited explanations for the cause of the disease and will further study the interaction between these genes and the environment in the future. (Source: Tian Ying, Xinhua News Agency)