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The second domestic MASP-2 inhibitor application for clinical application

 Last Update: 2022-01-12
 Source: Internet
 Author: User

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Article source: Medical Rubik's Cube Info

Author: Shi Bei

On December 3, the official website of CDE showed that the clinical application of Omeros's monoclonal antibody OMS721 (arsoplimab) injection targeting MASP-2 has been accepted by the State Food and Drug Administration.

The complement system plays a role in the inflammatory response and is activated due to tissue damage or microbial infection

Omeros has submitted a BLA application for OMS721 to the FDA for the treatment of thrombotic microangiopathy (HSCT-TMA) after hematopoietic stem cell transplantation.

In addition, OMS721 has also been developed for the treatment of IgA nephropathy.

The Phase III ARTEMIS-IGAN trial of OMS721 for the treatment of IgA nephropathy is ongoing

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