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"Patients with post-Covid-19 syndrome have no common features
.
The patients we see are young and old, mild and severe COVID cases, active and healthy, and some with pre-existing medical history," said Irina Petrache, MD, chief of the Division of Pulmonary Medicine at the National Jewish Health Center and co-author of the study
.
To that end, the researchers conducted exercise testing at the National Jewish Health Center for Post-COVID - 19 Care and Recovery, monitoring hundreds of data points when patients felt fatigued while on exercise bikes
.
They concluded that mitochondria -- the microorganisms in cells responsible for producing energy -- were not functioning properly in people with the long-term Covid-19 syndrome
.
While the test revealed dysfunction in muscle tissue, the researchers believe the same process is also associated with symptoms originating in the lungs and nervous system
.
The researchers hope the discovery will lead to a treatment for patients like Joanna Zieger
.
Five months after contracting Covid-19, she is still struggling with heart rate fluctuations, extreme fatigue and memory problems
.
"As soon as I started moving, my heart rate spiked, I couldn't focus and remember information, and it really affected my work and home life," Ziger said.
"
Exercise is also important for my mental health, It's hard to take that away
.
"
Ziger is working with doctors at National Jewish Health to improve her symptoms and hopes that all the tests and information she provides to learn the truth about her symptoms will also help others with post-Covid syndrome
.
The researchers will build on the current findings to better understand how the virus changes cells and how those effects can be reversed or repaired
.
Dr Petrache said there was still much unknown about COVID-19 and its long-term consequences, and prevention was as important as ever
.
Petrache said: "With the tests we have available here, and the great minds and curiosity of our doctors and researchers, we're going all out, and we're confident that we'll soon be able to provide those patients with post-coronavirus syndrome.
More answers
.
Decresed Fatty Acid Oxidation and Altered Lactate Production during Exercise in Patients with Post-acute COVID-19 Syndrome