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Clinical information, 1s reach
▎Clinical Questions: What is the risk of clinical heart failure (HF) with accompanying symptoms in patients with systemic sclerosis (SSc)? Literature screenshot ▎ Research plan: This retrospective cohort study conducted population matching and adopted Taiwan's provincial insurance database
.
At years 3, 5 and 10, patients were admitted to HF rates of 3.
5%, 5.
3% and 9.
7%,
respectively.
Patients with SSc had a higher risk of developing HF than individuals without SSc (HRs 3.
26, 95% CI 2.
49 to 4.
28).
Subgroup analyses showed that SSc had a greater effect on the development of HF in patients aged < 50 years ≥ than in patients aged 50 years (HR 7.
8, 95% CI 4.
03 to 15.
1 vs HR 2.
78, 95% CI 2.
06 to 3.
76).
<b10>
▎Conclusions and prospects: SSc is associated with a significantly increased risk of dominant clinical HF, and not only with asymptomatic ventricular dysfunction
.
4.
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